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婴幼儿配方奶粉中牛磺酸的检测研究进展

  • 王丙然 ,
  • 任德财 ,
  • 李星 ,
  • 屈岩峰
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  • 1(黑龙江东方学院,黑龙江 哈尔滨,150066);
    2(雅士利国际集团有限公司,广东 潮州,515638);
    3(哈尔滨学院,黑龙江 哈尔滨,150086)
硕士研究生(屈岩峰副教授为通讯作者,E-mail:quyanfeng01@sina.com)

收稿日期: 2020-04-17

  修回日期: 2020-07-14

  网络出版日期: 2020-12-11

Research progress of taurine detection in infant formula milk powder

  • WANG Bingran ,
  • REN Decai ,
  • LI Xing ,
  • QU Yanfen
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  • 1(East University of Heilongjiang,Harbin 150066,China);
    2(Yashili International Group co.LTD,Chaozhou 515638,China);
    3(Harbin University,Harbin 150086,China)

Received date: 2020-04-17

  Revised date: 2020-07-14

  Online published: 2020-12-11

摘要

牛磺酸是一种对婴幼儿发育具有重要作用的含硫氨基酸,其作为食品添加剂已应用于婴幼儿配方奶粉中。在婴幼儿配方奶粉中,牛磺酸作为可选择性添加元素,有严格的添加标准,从业人员极其重视对它的检测。近几年,有许多快捷、方便、准确的检测方法被报道,主要包括高效液相色谱法、氨基酸分析仪检测法、液相色谱和质谱联用检测法、毛细管电泳法。该文对国内外婴幼儿配方奶粉中牛磺酸的检测方法进行阐述,对于奶粉的样品处理、仪器、试剂、对环境的影响、方法的快速、简便、自动化程度进行分析,并对具有发展前景的牛磺酸检测方法进行预测。

本文引用格式

王丙然 , 任德财 , 李星 , 屈岩峰 . 婴幼儿配方奶粉中牛磺酸的检测研究进展[J]. 食品与发酵工业, 2020 , 46(22) : 287 -291 . DOI: 10.13995/j.cnki.11-1802/ts.024229

Abstract

Taurine is an important sulfur-containing amino acid that plays an important role in life activities.Taurine has been added as a food additive in infant formula,health food and beverage with a strict limitation to the amount of addition.So the detection of taurine is particularly important.The developed methods for the detection of taurine in food are high performance liquid chromatography,Amino acid analyzer,liquid chromatography and mass spectrometry and capillary electrophoresis.This paper explained the detection methods of taurine in infant formula at home and abroad,and analysed the sample treatment,instrument,reagent and environmental impact of infant formula,and the speed,simplicity,automation of the method,predicted the detection methods with development prospect in the future.

参考文献

[1] GE Z D,PRAVDIC D,BIENENGRAEBER M,et al.Isoflurane postconditioning protects against reperfusion injury by preventing mitochondrial permeability transition by an endothelial nitric oxide synthase-dependent mechanism[J].Anesthesiology,2010,112(1):73-85.
[2] DONOVAN S M.Human milk oligosaccharides:Potent weapons in the battle against rotavirus infection[J].Journal of Nutrition,2017,147(9):41-52.
[3] WO TATUM I V,KAPLAN P W,JALLON P,et al.Taurine[J].Advances in Experimental Medicine and Biology,2009,10(1):98-99.
[4] HU Yanli.Research progress of taurine[J].Heilongjiang Medicine Journal,2015(4):30-32.
[5] DONOHUE J.Hydrogen bonding and the zwitterion structure of taurine[J].Acta Crystallographica,2010,17(6):761-761.
[6] SUPAPORN KULTHINEE,SASIPA RAKMANCE, MICHAEL WYSS J.Taurine supplementation ameliorates the adverse effects of perinatal taurine depletion and high sugar intake on cardiac ischemia/reperfusion injury of adult female rats[J].Advances in Experimental Medicine and Biology,2017,975:741-755.
[7] KAYOKO SHIMADATAKAURA,KYOKO TAKAHASHI,TAKASHI ITO.Role for Taurine in Development of Oxidative Metabolism after Birth[M].United States:Kluwer Academic/Plenum Publishers,2017.
[8] IMAKI H,JACOBSON S G,KEMP C M,et al.Retinal morphology and visual pigment levels in 6-and 12-month-old rhesus monkeys fed a taurine-free human infant formula[J].Journal of Neuroscience Research,1993,36(3):290-304.
[9] 张茗晰,张萌,HARRIS RIPPS,等.牛磺酸的研究进展[J].黑龙江畜牧兽医,2015(7):76-78.
[10] HERNANDEZ BENITEZ,REYNA,VANGIPURAM S D,et al.Taurine enhances the growth of neural precursors derived from fetal human brain and promotes neuronal specification[J].Developmental Neuroscience,2013,35(1):40-49.
[11] GB 10765—2010 食品安全国家标准婴儿配方食品[S].北京:中国标准出版社,2010.
[12] 张峰.浅谈婴幼儿配方乳粉的标准法规、检测技术及监管制度[J].中国食品药品监管,2018(2):30-34.
[13] 孙成媛.中国与欧盟食品安全法律制度比较研究[D].乌鲁木齐:新疆大学,2017:20-30.
[14] GILL B D,INDYK H E,WOOLLARD D C.Current methods for the analysis of selected novel nutrients in infant formulas and adult nutritionals[J].Journal of AOAC International,2016,99(1):30-41.
[15] 黄金凤,寻知庆,汪晨霞,等.HPLC-MS/MS法测定婴幼儿配方乳粉中胆碱、左旋肉碱、牛磺酸与肌醇[J].分析测试学报,2018,37(6):702-707.
[16] CHEN Xiaofeng,ZHOU Wei,JIE Yingshuang.Ultra performance liquid chromatography-tandem mass spectrometry infant milk direct determination of taurine[J].Food Scieice,2015,36(24):280-285.
[17] 刘旭辉,刘萤,张姗,等.婴幼儿配方粉中牛磺酸的前处理优化及氨基酸分析仪分析[J].现代仪器与医疗,2016,22(5):92-94.
[18] 乳粉营养素标准并非越高越好[J].乳业科学与技术,2017,40(3):42.
[19] 郑国建,沈鸣,林毅侃,等.二维液相色谱法检测婴幼儿奶粉中的牛磺酸[J].中国乳品工业,2019,47(4):53-55;59.
[20] 刘建宇,李雅君,胡广红,等.高效液相色谱柱前衍生法测定乳粉中的牛磺酸[C].哈尔滨:中国乳制品工业协会年会,2006:40-42.
[21] 黄喆雯,唐钦强.2,4-二硝基氟苯柱前衍生高效液相色谱法测定婴幼儿配方乳粉中牛磺酸含量[J].食品科学,2008,29(3):381-383.
[22] 王晓莺,孙成均,张立实.9-氯甲酸芴甲酯柱前衍生高效液相色谱法测定奶粉中的牛磺酸[J].环境与职业医学,2009(3):87-90.
[23] 赵超敏,蒋颖婕,曾静.高效液相色谱法测定乳粉及液态奶中牛磺酸含量[J].现代食品科技,2019,35(1):211;258-262.
[24] YUAN Hui,GAO Shuai,WANG Chuanxing.Comparison of three methods for determinated taurine content in milk powder by pre-column derivatization[J].China Dairy Industry,2015,43(3):53-56.
[25] QIN Jing,WEI Xiang,CAI Weijiang,et al.Determination of taurine in branched amino acid powder by automatic amino acid analyzer[J].Journal of Food Safety &Quality,2017,8(5):1 883-1 887.
[26] 李菁,舒森,陈文彬.用氨基酸自动分析仪测定婴幼儿配方奶粉中的16种氨基酸[J].食品工业科技,2012(4):28-33.
[27] 蒲云月.氨基酸分析仪法测定奶粉中含硫氨基酸[J].农产品加工(学刊),2014(18):35-36.
[28] 刘常凯,何林飞,辛丽娜.氨基酸分析仪检测婴幼儿奶粉中牛磺酸含量[J].食品安全质量检测学报,2019,10(12):3 957-3 961.
[29] HUANG Hao,TAO Baohua,QI Chen,et al.Determination of choline,L-carnitine,acetyl-L-carnitine and taurine in human milk using UPLC-MS/MS[J].Journal of Food Safety &Quality,2014,5(7):2 060-2 064.
[30] 陈稚,揭新明,蔡康荣.高效液相色谱与电喷雾电离质谱联用测定婴儿配方奶粉中的牛磺酸和维生素[J].广东医学院学报,2007,25(3):252-254.
[31] ZHANG Ting,CHEN Lei,LIU Yun,et al.Determination of taurine in milk powder by high performance liquid chromatography-high resolution mass spectrometry[J].Journal of Food Safety &Quality,2017,8(6):2 086-2 090.
[32] CHEN Xiaofeng,ZHOU Wei,XIE Yingshuang.Direct determination of taurine in infant milk powder by ultra performance liquid chromatography-tandem mass spectrometry[J].Food Science,2015,36(24):280-285.
[33] KAPNISSI CHRISTODOULOU C P,ZHU X F,WARNER I M.Analytical separations in open-tubular capillary electrochromatography[J].Electrophoresis,2003,24(22-23):3 917-3 934.
[34] 丁晓静,田绪,李疆,等.毛细管区带电泳-间接紫外检测法测定婴儿配方奶粉中的胆碱[J].食品安全质量检测学报,2018,9(10):2 298-2 303.
[35] KLAMPFL C W,AHRER W.Determination of free amino acids in infant food by capillary zone electrophoresis with mass spectrometric detection[J].Electrophoresis,2001,22(8):1 579-1 584.
[36] 权菲菲.毛细管电泳-电容耦合非接触式电导检测法免标记分析食品中的牛磺酸[C].第21届全国色谱学术报告会及仪器展览会会议论文集.兰州:中国化学会,2017:340.
[37] EELTINK S,KOK W T.Recent applications in capillary electrochromatography[J].Electrophoresis,2006,27(1):84-96.
[38] 王红勇.薄层荧光色谱扫描测定奶粉中黄曲霉毒素M1及其展开剂的选择[J].中国卫生检验杂志,1993(4):221-222;234.
[39] 张忠义,刘振林,陈辉.乳与乳制品中牛磺酸的吸光光度法测定[J].中国公共卫生,2005(12):1 461.
[40] 陈秀明,刘青,董洁,等.婴幼儿配方奶粉中必要营养素的近红外光谱快速检测方法:中国,CN107655852A[P].2018-02-02.
[41] LIN Yuzhou,HUANG Yaoyao,CONG Xiao,et al.Rapid determination of taurine in milk powder by high performance liquid chromatography with on-line automated pre-column derivatization[J].Journal of Dairy Science and Technology,2015,38(5):21-23.
[42] LIU Yafeng,ZHU Weixia,YUAN Ping,et al.Determination of taurine contents in infant formula[J].China Dairy Industry,2010,38(2):52-54.
[43] 祖如松.食品中牛磺酸的测定方法——薄层层析法[J].中国卫生检验杂志,1998,8(5):292.
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