[1] KOGAN G,SOLTÉS L,STERN R,et al.Hyaluronic acid:A natural biopolymer with a broad range of biomedical and industrial applications[J].Biotechnol Lett,2007,29(1):17-25.
[2] POGREL M A,LOW M A,STERN R.Hyaluronan (hyaluronic acid) and its regulation in human saliva by hyaluronidase and its inhibitors[J].Journal of Oral Science,2003,45(2):85-91.
[3] 张天民,凌沛学,沈渤江,等.透明质酸的研制及应用研究[J].中国药学杂志,1987(9):56-59.
ZHANG T M,LING P X,SHEN B J,et al.Development and application of hyaluronic acid[J].Chinese Journal of Pharmaceuticals,1987(9):56-59.
[4] GARANTZIOTIS S,SAVANI R C.Hyaluronan biology:A complex balancing act of structure,function,location and context[J].Matrix Biology:Journal of the International Society for Matrix Biology,2019,78-79:1-10.
[5] ATHAMNEH T,AMIN A,BENKE E,et al.Alginate and hybrid alginate-hyaluronic acid aerogel microspheres as potential carrier for pulmonary drug delivery[J].The Journal of Supercritical Fluids,2019,150:49-55.
[6] KANDEL L,AGAR G,ELKAYAM O,et al.A novel approach for knee osteoarthritis using high molecular weight hyaluronic acid conjugated to plasma fibrinogen-interim findings of a double-blind clinical study[J].Heliyon,2020,6(7):e 04 475.
[7] TOLBA Y M,OMAR S S,NAGUI D A,et al.Effect of high molecular weight hyaluronic acid in treatment of osteoarthritic temporomandibular joints of rats[J].Archives of Oral Biology,2020,110:104 618.
[8] MOCHIZUKI T,IKARI K,YANO K,et al.Comparison of patient-reported outcomes of treatment with low-and intermediate molecular weight hyaluronic acid in Japanese patients with symptomatic knee osteoarthritis:A prospective,randomized,single-blind trial[J].Asia-Pacific Journal of Sports Medicine,Arthroscopy,Rehabilitation and Technology,2020,21:22-26.
[9] 白云,许国明,范明明,等.透明质酸和硅胶假体在美容整形隆鼻术中应用效果对比观察[J].智慧健康,2019,5(18):145-146.
BAI Y, XU G M, FAN M M,et al.Comparative observation of application effects of hyaluronic acid and silicone prosthesis in cosmetic rhinoplasty[J].Smart Health,2019,5(18):145-146.
[10] JOHNS M R,GOH L T,OEGGERLI A.Effect of pH,agitation and aeration on hyaluronic acid production by Streptococcus zooepidemicus[J].Biotechnology Letters,1994,16(5):507-512.
[11] KIM J H,YOO S J,OH D K,et al.Selection of a Streptococcus equi mutant and optimization of culture conditions for the production of high molecular weight hyaluronic acid[J].Enzyme and Microbial Technology,1996,19(6):440-445.
[12] 李志敏.高分子量透明质酸发酵工艺的研究[D].石家庄:河北科技大学,2015.
LI Z M.Study on fermentation process of high-molecular-weight hyaluronic acid[D].Shijiazhuang:Hebei University of Science and Technology,2015.
[13] 汪伟,蔡海波,谭文松.pH调控方式和温度对透明质酸发酵过程的影响[J].现代食品科技,2019,35(8):207-213.
WANG W,CAI H B,TAN W S.Effects of pH control modes on hyaluronic acid fermentation process[J].Modern Food Science and Technology,2019,35(8):207-213.
[14] WANG Y,HU L,HUANG H,et al.Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum[J].Nature Communications,2020,11(1):3 120.
[15] 刘龙.兽疫链球菌发酵生产透明质酸过程控制与优化[D].无锡:江南大学,2009.
LIU L.Control and optimization of production process of hyaluronic acid from Streptococcus epizoides fermentation[D].Wuxi:Jiang Nan University,2009.
[16] JAGANNATH S,RAMACHANDRAN K B.Influence of competing metabolic processes on the molecular weight of hyaluronic acid synthesized by Streptococcus zooepidemicus[J].Biochemical Engineering Journal,2010,48(2):148-158.
[17] MAT DON M,SHOPARWE N.Kinetics of hyaluronic acid production by Streptococcus zooepidemicus considering the effect of glucose[J].Biochemical Engineering Journal,2010,49(1):95-103.
[18] 吴祥坤,王腾飞,李丕武.葡萄糖浓度及补料方式对透明质酸发酵的影响[J].食品工业科技,2016,37(13):198-201;270.
WU X K,WANG T F,LI P W.Effect of glucose concentration and feeding methods on hyaluronic acid fermentation[J].Science and Technology of Food Industry,2016,37(13):198-201;270.
[19] LIU L,LIU Y,LI J,et al.Microbial production of hyaluronic acid:current state,challenges,and perspectives[J].Microbial Cell Factories,2011,10(99):2-9.
[20] ARMSTRONG D C,COONEY M J,JOHNS M R.Growth and amino acid requirements of hyaluronic-acid-producing Streptococcus zooepidemicus[J].Applied Microbiology and Biotechnology,1997,47(3):309-312.
[21] TLAPAK-SIMMONS V L,BARON C A,WEIGEL P H.Characterization of the purified hyaluronan synthase from Streptococcus equisimilis[J].Biochemistry,2004,43(28):9 234-9 242.
[22] PUMMILL P E,DEANGELIS P L.Alteration of polysaccharide size distribution of a vertebrate hyaluronan synthase by mutation[J].Journal of Biological Chemistry,2003,278(22):19 808-19 814.
[23] WEIGEL P H,DEANGELIS P L.Hyaluronan synthases:A decade-plus of novel glycosyltransferases[J].The Journal of Biological Chemistry,2007,282(51):36 777-36 781.
[24] MEDINA A P,LIN J,WEIGEL P H.Hyaluronan synthase mediates dye translocation across liposomal membranes[J].BMC Biochemistry,2012,13(1):2-5.
[25] 温琦,刘登如,陈坚,等.添加表面活性剂促进兽疫链球菌高产透明质酸[J].化工进展,2006,25(9):1 089-1 094.
WEN Q,LIU D R,CHEN J.et al.Enhancement of hyaluronic acid production by Streptococcus zooepidemicus H24 through supplement of CTAB[J].Chemical Industry and Engineering Progress,2006,25(9):1 089-1 094
[26] AMADO I R,VÁZQUEZ J A,PASTRANA L,et al.Microbial production of hyaluronic acid from agro-industrial by-products:Molasses and corn steep liquor[J].Biochemical Engineering Journal,2017,117:181-187.
[27] AMADO I R,VÁZQUEZ J A,PASTRANA L,et al.Cheese whey:A cost-effective alternative for hyaluronic acid production by Streptococcus zooepidemicus[J].Food Chemistry,2016,198:54-61.
[28] BLANK L M,HUGENHOLTZ P,NIELSEN L K.Evolution of the hyaluronic acid synthesis (has) operon in Streptococcus zooepidemicus and other pathogenic Streptococcius[J].Journal of Molecular Evolution,2008,67(1):13.
[29] HMAR R,PRASAD S,JAYARAMAN G,et al.Chromosomal integration of hyaluronic acid synthesis (has) genes enhances the molecular weight of hyaluronan produced in Lactococcus lactis[J].Biotechnology Journal,2014,9(12):1 554-1 564.
[30] CHIEN L J,LEE C K.Enhanced hyaluronic acid production in Bacillus subtilis by coexpressing bacterial hemoglobin[J].Biotechnology Progress,2007,23(5):1 017-1 022.
[31] PRASAD S,RAMACHANDRAN K,JAYARAMAN G.Transcription analysis of hyaluronan biosynthesis genes in Streptococcus zooepidemicus and metabolically engineered Lactococcus lactis[J].Applied Microbiology and Biotechnology,2012,94(6):1 593-1 607.
[32] YU H,STEPHANOPOULOS G.Metabolic engineering of Escherichia coli for biosynthesis of hyaluronic acid[J].Metabolic Engineering,2008,10(1):24-32.
[33] JIN P,KANG Z,YUAN P,et al.Production of specific-molecular-weight hyaluronan by metabolically engineered Bacillus subtilis 168[J].Metabolic Engineering,2016,35:21-30.
[34] CHEN W,MARCELLIN E,HUNG J,et al.Hyaluronan molecular weight is controlled by UDP-N-acetylglucosamine concentration in Streptococcus zooepidemicus[J].Journal of Biological Chemistry,2009,284(27):1 800 7-1 801 4.
[35] JIA Y,ZHU J,CHEN X,et al.Metabolic engineering of Bacillus subtilis for the efficient biosynthesis of uniform hyaluronic acid with controlled molecular weights[J].Bioresource Technology,2013,132(132):427-431.
[36] 吴祥坤.产中等分子量透明质酸菌株的选育及发酵过程优化[D].济南:齐鲁工业大学,2016.
WU X K.Screening of moderate molecular weight hyaluronic acid producing strain and optimization of fermentation process[D].Jinan:Qilu University of Technology,2016.
[37] CHENG F,GONG Q,YU H,et al.High-titer biosynthesis of hyaluronic acid by recombinant Corynebacterium glutamicum[J].Biotechnology Journal,2015,11(4):574-584.
[38] XU P,LI L Y,ZHANG F M,et al.Improving fatty acids production by engineering dynamic pathway regulation and metabolic control[J].Proceedings of the National Academy of Sciences of the United States of America,2014,111(31):27-31.
[39] MCNERNEY M P,WATSTEIN D M,STYCZYNSKI M P.Precision metabolic engineering:The design of responsive,selective,and controllable metabolic systems[J].Metabolic Engineering,2015,31:123-131.
[40] 张晋宇.表达phbCAB基因对兽疫链球菌中乳酸及透明质酸产量的影响[D].北京:清华大学,2005.
ZHANG J Y.Effect of expressing PHB synthesis gens phbCAB gene on production of latate and hyaluronic acid by Streptococcus zooepidemicus[D].Beijing:Tsinghua University,2005.
[41] KUMARI K,TLAPAK-SIMMONS V,BAGGENSTOSS B,et al.The Streptococcal hyaluronan synthases are inhibited by sulfhydryl-modifying reagents,but conserved cysteine residues are not essential for enzyme function[J].The Journal of Biological Chemistry,2002,277(16):13 943-13 951.
[42] BINER O,TRACHSEL C,MOSER A,et al.Isolation,N-glycosylations and function of a hyaluronidase-like enzyme from the venom of the spider Cupiennius salei[J].PloS One,2015,10(1):e 0143 963.
[43] JIN P,KANG Z,ZHANG N,et al.High-yield novel leech hyaluronidase to expedite the preparation of specific hyaluronan oligomers[J].Scientific Reports,2014,4(1):4 471.
[44] VALCARCEL J,GARCÍA M R,VARELA U R,et al.Hyaluronic acid of tailored molecular weight by enzymatic and acid depolymerization[J].International Journal of Biological Macromolecules,2020,145:788-794.
[45] FOX J.A brief review of the scientific history of several lesser-known snake venom proteins:L-amino acid oxidases,hyaluronidases and phosphodiesterases[J].Toxicon:Official Journal of the International Society on Toxinology,2012,62(1):75-82.