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天然糖蛋白研究进展

  • 唐嘉诚 ,
  • 包建强 ,
  • 陈彦婕 ,
  • 黄可承 ,
  • 宫萱 ,
  • 单钱艺
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  • 1(上海海洋大学 食品学院,上海,201306)
    2(上海水产品加工及贮藏工程技术研究中心,上海,201306)
    3(农业部水产品贮藏保鲜质量安全风险评估实验室(上海),上海,201306)
    4(上海市质量监督检验技术研究院,国家食品质量监督检验中心,上海,200233)
第一作者:硕士研究生(包建强教授为通信作者,E-mail:baojq@shou.edu.cn)

收稿日期: 2022-03-05

  修回日期: 2022-03-31

  网络出版日期: 2022-08-19

The research progress of natural glycoprotein

  • TANG Jiacheng ,
  • BAO Jianqiang ,
  • CHEN Yanjie ,
  • HUANG Kecheng ,
  • GONG Xuan ,
  • SHAN Qianyi
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  • 1(College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China)
    2(Shanghai Engineering Research Center of Aquatic Product Processing and Preservation, Shanghai 201306, China)
    3(Ministry of Agriculture Laboratory for Quality, Safety and Risk Assessment of Storage and Preservation of Aquatic Product(Shanghai), Shanghai 201306, China)
    4(Shanghai Institute of Quality Supervision and Inspection Technology, National Food Quality Supervision and Inspection Center, Shanghai 200233, China)

Received date: 2022-03-05

  Revised date: 2022-03-31

  Online published: 2022-08-19

摘要

糖蛋白是一种由多肽链与寡糖通过共价键相连而成的一类结合蛋白,具有糖和蛋白质2种特性,并且在自然界中广泛存在。基于天然糖蛋白抗肿瘤、抗氧化、免疫调节等众多生物活性以及来源广泛的特点,天然糖蛋白的开发利用和研究对食品药物研发具有十分重要的意义。该文对糖蛋白生物活性功能以及天然糖蛋白提取、分离纯化技术以及其结构分析表征的方法进行概述,为未来糖蛋白基础研究应用提供参考。

本文引用格式

唐嘉诚 , 包建强 , 陈彦婕 , 黄可承 , 宫萱 , 单钱艺 . 天然糖蛋白研究进展[J]. 食品与发酵工业, 2022 , 48(14) : 345 -353 . DOI: 10.13995/j.cnki.11-1802/ts.031414

Abstract

Glycoprotein is a kind of binding protein formed by a covalent bond between oligosaccharide chain and protein. It has the characteristics of both protein and polysaccharide and a variety of biological activities, such as anti-oxidation, anti-fatigue, anti-tumor, antibacterial and immunomodulatory functions. It also participates in mutual recognition between cells. Because of their unique biological activities, such as anti-tumors, anti-fatigue, antioxidant and immunomodulatory functions, glycoproteins have become a hot research topic in the disciplines of food science, immunology, medicine, and biochemistry. Glycoproteins are widely found in animals, plants, and microorganisms. An overview of the bioactive functions of glycoproteins was given in this paper, and the existing techniques for extraction and purification of glycoproteins as well as their physicochemical characterizationwere analyzed.Moreover, their development prospects, which will provide a reference for basic research and application of glycoprotein in the future.

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