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羧甲基化修饰多糖及其应用研究进展

  • 张舒婷 ,
  • 黄凯 ,
  • 轩华龙 ,
  • 牟腊梅 ,
  • 王心凌 ,
  • 唐华丽 ,
  • 邱顺丽
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  • 1(重庆三峡学院 生物与食品工程学院,重庆,404100)
    2(渝东北特色生物资源开发利用工程中心,重庆,404100)
第一作者:硕士研究生(唐华丽教授为通信作者,E-mail:hualidfood@163.com)

收稿日期: 2025-01-06

  修回日期: 2025-03-25

  网络出版日期: 2025-10-27

基金资助

重庆市自然科学基金面上项目(CSTB2022NSCQ-MSX1661);重庆市教委科研项目(KJQN202201216)

Research progress of carboxymethylated polysaccharide and its application

  • ZHANG Shuting ,
  • HUANG Kai ,
  • XUAN Hualong ,
  • MU Lamei ,
  • WANG Xinling ,
  • TANG Huali ,
  • QIU Shunli
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  • 1(School of Biological and Food Engineering, Chongqing Three Gorges University,Chongqing 404100, China)
    2(Special Biological Resources Development and Utilization of Engineering Center of Northeast Chongqing, Chongqing 404100, China)

Received date: 2025-01-06

  Revised date: 2025-03-25

  Online published: 2025-10-27

摘要

作为构成生命体的重要组成部分之一,多糖具有多种生物活性,其生物活性受结构影响,且其特殊结构限制了其在加工和活性方面的应用。近年来,对天然多糖的结构进行修饰成为了研究的热点,羧甲基化修饰作为一种有效的化学改性策略,能够显著改善多糖的生物活性和应用特性。该文概述了羧甲基化多糖的合成路径和表征,探讨了羧甲基化修饰对多糖结构、生物活性的影响及其在食品工业和生物医药领域中的应用。旨在为羧甲基化多糖的研发与应用提供理论参考,促进多糖修饰领域的进展。

本文引用格式

张舒婷 , 黄凯 , 轩华龙 , 牟腊梅 , 王心凌 , 唐华丽 , 邱顺丽 . 羧甲基化修饰多糖及其应用研究进展[J]. 食品与发酵工业, 2025 , 51(20) : 414 -426 . DOI: 10.13995/j.cnki.11-1802/ts.042057

Abstract

Polysaccharides, serving as a pivotal constituent in life forms, exhibit diverse biological activities that are intricately tied to their structural configurations.However, their unique structural attributes pose constraints on their utilization in terms of processing and activity.Recently, the modification of natural polysaccharide structures has garnered significant research attention.Among these strategies, carboxymethylation stands out as an efficacious chemical modification approach, capable of markedly enhancing the biological activities and practical applications of polysaccharides.This review delineates the synthetic pathways and characterization methods of carboxymethylated polysaccharides, while also examining the effects of carboxymethylation on the structure and biological activities of polysaccharides, alongside its applications within the food industry and biomedical sector.The objective is to offer a theoretical framework for the research and application of carboxymethylated polysaccharides, thereby fostering advancements in the realm of polysaccharide modification.

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