Abstract: Hyperglycemia is a common risk factor of many chronic diseases, plasma glucose regulating is also an important method for preventing and treating chronic diseases.As a natural active substance, tannins widely exist in plants and have an outstanding activity on plasma glucose regulating.The classification, extraction and bioactive functions of plant tannins were briefly described, focusing on the mechanism of plasma sugar regulating the activity of plant tannins.Plant tannins can delay carbohydrate absorption by inhibiting the activities of α-glucosidase and α-amylase, improved insulin resistance by promoting the expression of glucose transporter 4 and improving the transport capacity of glucose, affect the phosphorylation level of tyrosine protein to promote the ability of cells to uptake glucose by activating tyrosine kinase activity.However, there were few reports on the inhibition of gluconeogenesis and the promotion of glycolysis, indicating a breakthrough point in the study of blood glucose regulation activity of tannin.
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