Abstract: Chinese wolfberry,red jujube and seabuckthorn were chosen as the raw materials to prepare healthy compound beverage. The juice was through crushing,mixing,homogenizing and sterilizing. The best ratio of wolfberry,red jujube and seabuckthorn juice( 3∶ 2∶ 2) was determined by orthogonal experiment,and then the best formula of three fruits compound beverage was optimized by orthogonal experiment. The result showed that the best composition of the beverage was 40% of three fruits juice,6% sugar,0. 02% citric acid and 0. 14% compound stabilizer.The compound beverage is not only full of nutrition,but also has characteristic flavor of wolfberry,red jujube and seabuckthorn.