The effect of garlic extract on the development of biofilm in Pseudomonas aeruginosa PAO1 was studied.The biofilm production and factors correlated with the biofilm formation in PAO1 were evaluated.The results showed that the garlic extract not only inhibited the development of biofilm,extracellular polysaccharide production,and motility characteristic,but also had synergistic effect with Azithromycin when the concentration of garlic extractdidn't affect growth of PAO1.The results suggested that garlic extract could inhibit the development of biofilm and reduce the expression of factors correlated with the biofilm formation in P.aeruginosa PAO1 by interfering with their QS systems.
DING Rong-rong,CHEN Gui-tang,YANG Zhi-ping,WANG Hai-xiang,QI Guo-hong.
Effect of garlic extract on development of biofilm in Pseudomonas aeruginosa[J]. Food and Fermentation Industries, 2017, 43(2): 85