研究报告

植物乳杆菌PMO的安全性分析

  • 王春幸 ,
  • OHYOUNGJOO ,
  • 甘奕 ,
  • KIMTAESUK ,
  • 李洪军 ,
  • IKHYUNYEO ,
  • 贺稚非
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  • 1(西南大学 食品科学学院,重庆,400715);
    2(韩国圃美多有限责任公司,首尔,120-749)
第一作者:硕士研究生(贺稚非教授为通讯作者,E-mail:2628576386@qq.com)

收稿日期: 2020-02-23

  修回日期: 2020-04-21

  网络出版日期: 2020-11-02

基金资助

西南大学国际合作项目(20131220)

Safety analysis of Lactobacillus plantarum strain PMO

  • WANG Chunxing ,
  • OH YOUNG JOO ,
  • GAN Yi ,
  • KIM TAE SUK ,
  • LI Hongjun ,
  • IK HYUN YEO ,
  • HE Zhifei
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  • 1(College of Food Science, Southwest University,Chongqing 400715,China);
    2(Korea Pulmuone Limited Liability Company,Shouer 120-749,Korea)

Received date: 2020-02-23

  Revised date: 2020-04-21

  Online published: 2020-11-02

摘要

为获得新的优良菌株,对从韩国泡菜中分离筛选的植物乳杆菌PMO(Lactobacillus plantarum PMO)进行安全性评价。对小鼠急性毒性、抗生素敏感性、细菌易位、脏器指数、生化指标等进行测定,结果表明,L.plantarum PMO无急性毒性,对四环素、红霉素和庆大霉素等抗生素高度敏感,不会引起沙门氏菌和志贺氏菌细菌易位。灌胃L.plantarum PMO小鼠的脏器指数及生化指标与对照小鼠无显著差异,对肝脏、心脏、肾脏及胆道的细胞和功能均无损害作用。

本文引用格式

王春幸 , OHYOUNGJOO , 甘奕 , KIMTAESUK , 李洪军 , IKHYUNYEO , 贺稚非 . 植物乳杆菌PMO的安全性分析[J]. 食品与发酵工业, 2020 , 46(19) : 28 -34 . DOI: 10.13995/j.cnki.11-1802/ts.023725

Abstract

The safety of Lactobacillus plantarum strain PMO isolated from kimchi was evaluated. The acute toxicity, antibiotic sensitivity, bacterial translocation, organ index and biochemical index in mice were determined. Results showed that no acute toxicity was detectable, high sensitivities to tetracycline, erythromycin and gentamicin were identified, and bacterial translocation of Salmonella and Shigella was not observed. The organ indexes and biochemical indexes of L. plantarum PMO treated mice were not significantly different from that of the control group. L. plantarum PMO did not exhibit damage on the cells and functions of the liver, heart, kidney and biliary tract.

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