随着静息细胞产率的提高和大量静息产物的生成,利用静息细胞培养体系使细胞不能继续繁殖转为静息状态,此时各种酶在代谢过程中起作用发酵生成营养物的静息细胞法成为近几年研究的热点。文中对静息细胞的研究现状、工艺优势、培养系统、静息细胞的代谢过程等进行了综述,并提出了该领域面临的问题,对未来的发展进行了展望。

With the increasingly resting cell rate and resting cell products,production of resting cell fermentation had been a research topic due to cells can't be propagated in resting cell culture system and thus can be converted to resting state.There are a variety of enzyme systems at work.Present research achievements,crafts advantages,culture systems and resting cell of metabolic processes were reviewed in this article,which also referred to unsolved problems in this field so far and the orient of development in future.