采用液相色谱串联质谱法测定了多种食品中的全氟丁烷磺酸、全氟己烷磺酸、全氟辛烷磺酸、全氟癸烷磺酸、全氟己酸、全氟癸酸、全氟辛酸、全氟壬酸、全氟十一酸、全氟十二酸、全氟十三酸、全氟十四酸、全氟丁酸、全氟戊酸、全氟庚酸的含量,并选择离子检测进行阳性验证,采用离子对液液萃取法(LLE)和固相萃取法(SPE)处理,定容后供液相色谱-质谱/质谱仪测定和验证,外标法定量。该方法的最低检出限、线性范围和方法回收率分别为,1μg/kg、1~100μg/L和76.50%~110.00%。

In this paper,liquid chromatography tandem mass spectrometry was used to determine perfluorobutanesulfonate,perfluorohexanesulfonate,perfluorooctanesulfonate,perfluorodecanesulfonate,perfluorohexanoate,perfluorodecanoate,perfluorooctanoate,perfluorononanoate,perfluoroundecanoate,perfluorododecanoate,perfluorotridecanoic acid,perfluoro tetradecanoict acid,perfluoro heptafluorobutyric acid,Perfluoropentanoic acid,Perfluoroheptanoic acid of residues in a variety of food with ion monitoring for positive confirmation. Sample was extracted with liquid-liquid extraction( LLE) and solid phase extraction( SPE) process. Eluted sample was determined by LC-MS /MS using external method. The detection limits,linear ranges,and recoveries were 1 μg / kg,1 ~ 100 μg / L and76. 50% ~ 110. 00%. This study established a method for determination of fluorocarbon surfactant in food. It is quickly,sensitive and can simultaneously determine many kinds of fluorocarbon surfactant and their positive confirmations.