[1] 陈宁.氨基酸工艺学[M].第二版.北京:中国轻工业出版社,2020.
CHEN N.Amino acid technology[M].Second Edition.Beijng:China Light Industry Press,2020.
[2] LI Y J,WEI H B,WANG T,et al.Current status on metabolic engineering for the production of L-aspartate family amino acids and derivatives[J].Bioresource Technology,2017,245(Pt B):1 588-1 602.
[3] GU C S,MAO X B,CHEN D W,et al.L-isoleucine plays an important role for maintaining immune function[J].Current Protein Peptide Science,2019,20(7):644-651.
[4] BECKER J,GIESSELMANN G,HOFFMANN S L,et al.Corynebacterium glutamicum for sustainable bioproduction:From metabolic physiology to systems metabolic engineering[J].Advances Biochemical Engineer Biotechnology,2018,162:217-263.
[5] KORTHIKUNTA V,PANDEY J,SINGH R,et al.In vitro anti-hyperglycemic activity of 4-hydroxyisoleucine derivatives[J].Phytomedicine,2015,22(1):66-70.
[6] ZHANG C L,MA J,LI Z X,et al.A strategy for L-isoleucine dioxygenase screening and 4-hydroxyisoleucine production by resting cells[J].Bioengineered,2018,9(1):72-79.
[7] D'ESTE M,ALVARADO-MORALES M,ANGELIDAKI I.Amino acids production focusing on fermentation technologies-A review[J].Biotechnology Advances,2018,36(1):14-25.
[8] YAMAMOTO K,TSUCHISAKA A,YUKAWA H.Branched-chain amino acids[J].Advances Biochemical Engineer Biotechnology,2017,159:103-128.
[9] DONG X Y,ZHAO Y,ZHAO J X,et al.Characterization of aspartate kinase and homoserine dehydrogenase from Corynebacterium glutamicum IWJ001 and systematic investigation of L-isoleucine biosynthesis[J].Journal of Industrial Microbiology and Biotechnology,2016,43(6):873-885.
[10] PARK J H,OH J E,LEE K H,et al.Rational design of Escherichia coli for L-isoleucine production[J].ACS Synthetic Biology,2012,1(11):532-540.
[11] YOKOTA A,SAWADA K,WADA M.Boosting anaplerotic reactions by pyruvate kinase gene deletion and phosphoenolpyruvate carboxylase desensitization for glutamic acid and lysine production in Corynebacterium glutamicum[J].Advances in Biochemical Engineering-Biotechnology,2017,159:181-198.
[12] 朱福周, 芦楠,李宇虹.增强回补途径对谷氨酸棒状杆菌合成L-异亮氨酸的影响[J].食品与发酵工业,2020,46(2):11-17.
ZHU F,LU N,LI Y.Comparing effects of enhancing anaplerotic pathways on L-isoleucine production performance by Corynebacterium glutamicum YI[J].Food and Fermentation Industries,2020,46(2):11-17.
[13] ZHAO L,LU Y,YANG J,et al.Expression regulation of multiple key genes to improve L-threonine in Escherichia coli [J].Microbial Cell Factories,2020,19(1):46.
[14] QIN T,HU X Q,HU J Y,et al.Metabolic engineering of Corynebacterium glutamicum strain ATCC13032 to produce L-methionine[J].Biotechnology and Applied Biochemistry,2015,62(4):563-573.
[15] PETIT C,KIM Y,LEE S K,et al.Reduction of feedback inhibition in homoserine kinase (ThrB) of Corynebacterium glutamicum enhances L-threonine biosynthesis[J].ACS Omega,2018,3(1):1 178-1 186.
[16] GUO Y,XU J,HAN M,et al.Generation of mutant threonine dehydratase and its effects on L-isoleucine synthesis in Corynebacterium glutamicum[J].World Journal of Microbiology and Biotechnology,2015,31(9):1 369-1 377.
[17] 张海灵, 李颜颜,王小元.代谢工程改造谷氨酸棒状杆菌合成及分泌途径生产L-缬氨酸[J].生物工程学报,2018,34(10):1 606-1 619.
ZHANG H,LI Y,WANG X.Metabolic engineering of L-valine synthesis and secretory pathways in Corynebacterium glutamicum for higher production[J].Chinese Journal of Biotechnology,2018,34(10):1 606-1 619.
[18] MORBACH S,JUNGER C,SAHM H,et al.Attenuation control of ilvBNC in Corynebacterium glutamicum:evidence of leader peptide formation without the presence of a ribosome binding site[J].Journal of Bioscience and Bioengineering,2000,90(5):501-507.
[19] ZHANG H L,LI Y Y,WANG C H,et al.Understanding the high L-valine production in Corynebacterium glutamicum VWB-1 using transcriptomics and proteomics[J].Scientific Reports,2018,8(1):3 632.
[20] VOGT M,KRUMBACH K,BANG W G,et al.The contest for precursors:Channelling L-isoleucine synthesis in Corynebacterium glutamicum without byproduct formation[J].Applied Microbiology and Biotechnology,2015,99(2):791-800.
[21] WANG J,WEN B,WANG J,et al.Enhancing (L)-isoleucine production by thrABC overexpression combined with alaT deletion in Corynebacterium glutamicum[J].Applied Biochemistry and Biotechnology,2013,171(1):20-30.
[22] GUILLOUET S,RODAL A,AN G H,et al.Metabolic redirection of carbon flow toward L-isoleucine by expressing a catabolic threonine dehydratase in a threonine-overproducing Corynebacterium glutamicum [J].Applied Microbiology and Biotechnology,2001,57(5-6):667-673.
[23] GUILLOUET S,RODAL A A,AN G,et al.Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on L-isoleucine production[J].Applied and Environmental Microbiology,1999,65(7):3 100-3 107.
[24] ZHANG Y,LIU Y,ZHANG S,et al.Metabolic engineering of Corynebacterium glutamicum WM001 to improve L-isoleucine production[J].Biotechnology and Applied Biochemistry,2020.DOI:10.1002/bab.1963.
[25] YIN L,HU X,XU D,et al.Co-expression of feedback-resistant threonine dehydratase and acetohydroxy acid synthase increase L-isoleucine production in Corynebacterium glutamicum [J].Metabolic Engineering,2012,14(5):542-550.
[26] DONG X Y,ZHAO Y,HU J Y,et al.Attenuating L-lysine production by deletion of ddh and lysE and their effect on L-threonine and L-isoleucine production in Corynebacterium glutamicum[J].Enzyme and Microbial Technology,2016,93-94:70-78.
[27] MA W J,WANG J L,LI Y,et al.Cysteine synthase A overexpression in Corynebacterium glutamicum enhances L-isoleucine production[J].Biotechnology and Applied Biochemistry,2019,66(1):74-81.
[28] YIN L,SHI F,HU X,et al.Increasing L-isoleucine production in Corynebacterium glutamicum by overexpressing global regulator Lrp and two-component export system BrnFE[J].Journal of Applied Microbiology,2013,114(5):1 369-1 377.
[29] XIE X X,XU L L,SHI J M,et al.Effect of transport proteins on L-isoleucine production with the L-isoleucine-producing strain Corynebacterium glutamicum YILW[J].Journal of Industrial Microbiology and Biotechnology,2012,39(10):1 549-1 556.
[30] ZHAO J X,HU X Q,LI Y,et al.Overexpression of ribosome elongation factor G and recycling factor increases L-isoleucine production in Corynebacterium glutamicum[J].Applied Microbiology and Biotechnology,2015,99(11):4 795-4 805.
[31] SHI F,LI K,HUAN X J,et al.Expression of NAD(H) kinase and glucose-6-phosphate dehydrogenase improve NADPH supply and L-isoleucine biosynthesis in Corynebacterium glutamicum ssp. lactofermentum[J].Applied Biochemistry and Biotechnology,2013,171(2):504-521.
[32] MA W J,WANG J L,LI Y,et al.Enhancing pentose phosphate pathway in Corynebacterium glutamicum to improve L-isoleucine production[J].Biotechnology and Applied Biochemistry,2016,63(6):877-885.
[33] SHI F,ZHANG S P,LI Y F,et al.Enhancement of substrate supply and ido expression to improve 4-hydroxyisoleucine production in recombinant Corynebacterium glutamicum ssp.lactofermentum[J].Applied Microbiology and Biotechnology,2019,103(10):4 113-4 124.
[34] TAN S,SHI F,LIU H,et al.Dynamic control of 4-hydroxyisoleucine biosynthesis by modified L-isoleucine biosensor in recombinant Corynebacterium glutamicum[J].ACS Synthetic Biology,2020,9(9):2 378-2 389.
[35] SHI F,ZHANG M L,LI Y F,et al.Sufficient NADPH supply and pknG deletion improve 4-hydroxyisoleucine production in recombinant Corynebacterium glutamicum[J].Enzyme and Microbial Technology,2018,115:1-8.
[36] KIVERO A D,NOVIKOVA A E,SMIRNOV S V.Modification of E.coli central metabolism to optimize the biotransformation of L-isoleucine into 4-hydroxyisoleucine by enzymatic hydroxylation[J].Applied Microbiology and Biotechnology,2012,48(7):639-644.
[37] SHI F,NIU T F,FANG H M.4-Hydroxyisoleucine production of recombinant Corynebacterium glutamicum ssp.lactofermentum under optimal corn steep liquor limitation[J].Applied Microbiology and Biotechnology,2015,99(9):3 851-3 863.
[38] SHI F,FANG H M,NIU T F,et al.Overexpression of ppc and lysC to improve the production of 4-hydroxyisoleucine and its precursor L-isoleucine in recombinant Corynebacterium glutamicum ssp. lactofermentum[J].Enzyme and Microbial Technology,2016,87-88:79-85.
[39] ZHANG C L,LI Y J,MA J,et al.High production of 4-hydroxyisoleucine in Corynebacterium glutamicum by multistep metabolic engineering[J].Metabolic Engineering,2018,49:287-298.
[40] JEON J M,KIM H J,BHATIA S K,et al.Application of acetyl-CoA acetyltransferase (AtoAD) in Escherichia coli to increase 3-hydroxyvalerate fraction in poly (3-hydroxybutyrate-co-3-hydroxyvalerate)[J].Bioprocess and Biosystems Engineering,2017,40(5):781-789.
[41] MA W J,WANG J L,LI Y,et al.Poly (3-hydroxybutyrate-co-3-hydroxyvalerate) co-produced with L-isoleucine in Corynebacterium glutamicum WM001[J].Microbial Cell Factory,2018,17(1):93.
[42] HASHIGUCHI K,MATSUI H,KURAHASHI O.Effects of a feedback-resistant aspartokinase III gene on L-isoleucine production in Escherichia coli K-12[J].Bioscience Biotechnology and Biochemistry,1999,63(11):2 023-2 024.
