综述与专题评论

疏水性功能性因子纳米包埋体系研究进展

  • 魏雪林 ,
  • 钟艳 ,
  • 刘雪 ,
  • 刘磊 ,
  • 王力均 ,
  • 陈祥贵 ,
  • 王芹 ,
  • 杨潇
展开
  • (西华大学 食品与生物工程学院,四川 成都, 610039)
硕士研究生(杨潇教授为通讯作者,E-mail:13076014204@163.com)

收稿日期: 2020-09-16

  修回日期: 2020-11-17

  网络出版日期: 2021-08-20

基金资助

国家自然科学基金面上项目(31972009);四川省科技厅重点研发(2020YFN0153);西华大学研究生创新基金(SA2000002953)

Review of hydrophobic functional factor nano-embedding system

  • WEI Xuelin ,
  • ZHONG Yan ,
  • LIU Xue ,
  • LIU Lei ,
  • WANG Lijun ,
  • CHEN Xianggui ,
  • WANG Qin ,
  • YANG Xiao
Expand
  • (School of Food and Biological Engineering, Xihua University, Chengdu 610039, China)

Received date: 2020-09-16

  Revised date: 2020-11-17

  Online published: 2021-08-20

摘要

具有生物活性的疏水功能因子对人体健康具有益处。但因其较弱的极性和外层分布的疏水基团使其水溶性和在体内的生物利用度较低,限制了其在功能性食品中的应用。为改善这类因子的水溶性和提高其生物利用度,可通过采用一种或多种亲水性物质将疏水性功能因子包埋在其核心,将其制备成纳米级稳定亲水体系。该综述中,对近几年基于糖类、蛋白类、脂质类等不同包材的疏水功能因子纳米体系进行了阐述,并对疏水性功能因子纳米体系的不同包埋技术进行了比较;同时阐述了功能因子纳米包埋体系的功能特性、体内吞噬机制及疏水性功能因子纳米体系在体内外研究的差异。

本文引用格式

魏雪林 , 钟艳 , 刘雪 , 刘磊 , 王力均 , 陈祥贵 , 王芹 , 杨潇 . 疏水性功能性因子纳米包埋体系研究进展[J]. 食品与发酵工业, 2021 , 47(14) : 300 -306 . DOI: 10.13995/j.cnki.11-1802/ts.025663

Abstract

The hydrophobic functional factor with biological activity is beneficial to human health. However, due to its weak polarity and hydrophobic groups distributed on the outer layer, its water solubility and bioavailability are low, which limits its application in functional foods. In order to improve the water solubility and increase bioavailability, the current research adopts one or several hydrophilic substances to embed the hydrophobic functional factors in the core and prepare a nano-scale stable hydrophilic system. In this review, the hydrophobic functional factors nano-systems based on saccharides, proteins, lipids and other materials in recent years were described, and the different embedding technologies of hydrophobic functional factors nano-systems were compared. At the same time, the functional characteristics, the phagocytic mechanism, and the differences in the studies on the hydrophobic functional factors nanosystems in vivo and in vitro were also be explored.

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