食品与发酵工业 >

2021 , Vol. 47 >Issue 15: 120 - 128

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.026615

研究报告

PET/PE复合膜中初级芳香胺及2种塑料添加剂的迁移研究及安全评估

  • 罗任杰 ,
  • 林勤保 ,
  • 颜建伟 ,
  • 马俊杰 ,
  • 李忠
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  • 1(暨南大学 包装工程研究所,广东 珠海,519070)
    2(华东交通大学 土木建筑学院,江西 南昌,330052)
    3(拱北海关技术中心,广东 珠海,519020)
硕士研究生(林勤保研究员和颜建伟教授为共同通讯作者,E-mail:tlinqb@jnu.edu.cn;tyanjianwei@jnu.edu.cn)

收稿日期: 2021-01-12

  修回日期: 2021-03-05

  网络出版日期: 2021-08-23

基金资助

国家重点研发计划项目(2018YFC1603206;2018YFC1603204);国家自然科学基金优青培育项目(20202ZDB01001);珠海进出口公共技术服务平台产学研协同创新计划(IETP202001006)

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Migration and safety assessment of primary aromatic amines and two plastic additives from PET/PE composite films

  • LUO Renjie ,
  • LIN Qinbao ,
  • YAN Jianwei ,
  • MA Junjie ,
  • LI Zhong
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  • 1(Packaging Engineering Institute,Jinan University,Zhuhai 519070,China)
    2(School of Civil Engineering and Architecture,East China Jiaotong University,Nanchang 330052,China)
    3(Gongbei Customs Technology Center,Zhuhai 519020,China)

Received date: 2021-01-12

  Revised date: 2021-03-05

  Online published: 2021-08-23

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摘要

首先对聚对苯二甲酸乙二醇酯/聚乙烯复合膜(polyethylene terephthalate/polyethylene composite film,PET/PE)及聚对苯二甲酸乙二醇酯/铝/聚乙烯复合膜(PET/AL/PE)的乙酸乙酯超声提取液进行筛查,确定高响应峰初级芳香胺(primary aromatic amines,PAAs)、4,4′-二氨基二苯硫醚、爽滑剂芥酸酰胺(erucamide,EAD)和抗氧剂2246作为目标检测物。结合筛查结果建立同时测定25种PAAs、EAD及抗氧剂2246的高效液相色谱-串联质谱方法:配制质量体积分数4%乙酸溶液、10%和95%的乙醇溶液作为食品模拟液,按照标准要求分别进行40 ℃/10 d以及70 ℃/2 h的迁移试验。浸泡液经过滤后直接进样,分别以H-ESI+和H-ESI-模式进行定量分析。3种食品模拟物中的25种PAAs及2种塑料添加剂标准品在其对应浓度范围线性良好,相关系数均大于0.997 3,各个物质在3个浓度水平的加标回收率范围为76.9%~108.2%,相对标准偏差为4%~12.5%;在40 ℃/10 d条件下2种复合膜中PAAs的迁移量为3~298 μg/L,在70 ℃/2 h下为3~118 μg/L;EAD在2种迁移条件下的迁移量为30~880 μg/L,抗氧剂2246迁移量为9~210 μg/L。迁移结果表明:40 ℃/10 d条件下迁移出的PAAs种类及迁移量均高出70 ℃/2 h条件下的迁移量;在较低使用温度(40 ℃)下,复合膜镀铝可以有效地减少芳香胺及添加物的迁出;pH值会对PAAs的迁移产生影响:PAAs更易于在中性和油性模拟物中迁出,在酸性模拟物中的迁移明显减弱。安全评估的结果为抗氧剂2246的迁移量低于国标和欧盟的限量,EAD的迁移量低于TTC法估算的安全阈值,而检出的芳香胺浓度均不能满足欧盟标准的要求,存在安全风险。

关键词： 初级芳香胺; 塑料复合包装; 塑料添加剂; 聚对苯二甲酸乙二醇酯/聚乙烯复合膜; 高效液相色谱-串联质谱法; 迁移; 食品安全

本文引用格式

罗任杰 , 林勤保 , 颜建伟 , 马俊杰 , 李忠 . PET/PE复合膜中初级芳香胺及2种塑料添加剂的迁移研究及安全评估[J]. 食品与发酵工业, 2021 , 47(15) : 120 -128 . DOI: 10.13995/j.cnki.11-1802/ts.026615

Abstract

Detection for PET/PE composite film was conducted by ultra high-performance liquid chromatography mass spectrometry (UPLC-MS/MS), and one primary aromatic amines (PAAs) Bis(4-aminophenyl) sulfide as well as two plastic additives erucamide (EAD) and antioxidant 2246 (AO2246) were detected. Then the migration of PET/PE and PET/AL/PE in composite films under 40 ℃/10 d and 70 ℃/2 h conditions immersed in three kinds of simulants (4% acetic acid, 10% and 95% ethanol) were carried out. The proposed method could simultaneously to determine 25 PAAs and EAD in ESI+ mode, and also to investigate AO2246 in ESI-mode. It was validated in terms of linearity, matrix effect error, detection and quantification limits, repeatability and intermediate precision. The quantitative method presented recoveries ranging from 82.7% to 119%, with a precision (RSD) lower than 12.5% for the 27 substances. Based on the experimental results, several conclusions were drawn as follows. Firstly, the species and amount of PAAs migrated at 40 ℃/10 d were higher than those at 70 ℃/2 h. And time was the main factor affecting PAAs’ migration and higher temperatures may lead to more PAAs released. Secondly, the migration of both PAAs could be effectively reduced by aluminum layer at a low temperature. Thirdly, the difference among the results in three kinds of simulants suggested that pH could also has an impact that acidic condition weakened PAAs’ migration. Last but not the least, the migration of EAD and AO2246 was lower than TTC safety threshold and national standard GB 9685 respectively. However, PAAs’ content could not meet the requirement of European Union standard, which indicates high safety risk.

Key words： primary aromatic amines; plastic composite packaging; plastic additives; PET/PE; high performance liquid chromatography mass spectrometry(HPLC-MS); migration; food safety

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