[1] CORNEJO-GARCÍA J A,PERKINS J R,JURADO-ESCOBAR R,et al.Pharmacogenomics of prostaglandin and leukotriene receptors[J].Frontiers in Pharmacology,2016,7:316.
[2] AHLMANN M,HEMPEL G.The effect of cyclophosphamide on the immune system:Implications for clinical cancer therapy[J].Cancer Chemotherapy and Pharmacology,2016,78(4):661-671.
[3] SHI Q L,CHEN L J.Cereblon:A protein crucial to the multiple functions of immunomodulatory drugs as well as cell metabolism and disease generation[J].Journal of Immunology Research,2017,2017:9130608.
[4] XU B,YE L,TANG Y,et al.Preparation and purification of an immunoregulatory peptide from Stolephorus chinensis of the East Sea of China[J].Process Biochemistry,2020,98:151-159.
[5] LIU P,LIAO W,QI X P,et al.Identification of immunomodulatory peptides from zein hydrolysates[J].European Food Research and Technology,2020,246(5):931-937.
[6] HOU H,FAN Y,LI B F,et al.Purification and identification of immunomodulating peptides from enzymatic hydrolysates of Alaska pollock frame[J].Food Chemistry,2012,134(2):821-828.
[7] 贺屹潮. 大鲵肉酶解肽制备及抗氧化与免疫调节活性研究[D].汉中:陕西理工大学,2020.
HE Y C.Preparation of enzymatic peptides from Chinese giant salamander(Andrias davidiauns) meat and its antioxidant and immunomodulatory activity activity[D].Hanzhong:Shaanxi University of Technology,2020.
[8] HOU H,FAN Y,WANG S.et al.Immunomodulatory activity of Alaska pollock hydrolysates obtained by glutamic acid biosensor-Artificial neural network and the identification of its active central fragment[J].Journal of Functional Foods,2016,24:37-47.
[9] YANG Q,CAI X,HUANG M.et al.A specific peptide with immunomodulatory activity from Pseudostellaria heterophylla and the action mechanism[J].Journal of Functional Foods,2020,68:103887.
[10] YANG Q,CAI X X,HUANG M C,et al.Isolation,identification,and immunomodulatory effect of a peptide from Pseudostellaria heterophylla protein hydrolysate[J].Journal of Agricultural and Food Chemistry,2020,68(44):12 259-12 270.
[11] 叶盛旺, 杨最素,李维,等.青蛤酶解多肽对RAW 264.7巨噬细胞的免疫调节作用[J].食品科学,2019,40(7):185-191.
YE S W,YANG Z S,LI W,et al.Immunomodulatory effects of peptides from enzymatic hydrolysate of Cyclina sinensis on RAW264.7 macrophages[J].Food Science,2019,40(7):185-191.
[12] LI W,YE S,ZHANG Z,et al.Purification and characterization of a novel Pentadecapeptide from protein hydrolysates of Cyclina sinensis and its immunomodulatory effects on RAW264.7 Cells[J].Marine Drugs,2019,17(1):30.
[13] SANTIAGO-LÓPEZ L,HERNÁNDEZ-MENDOZA A,VALLEJO-CORDOBA B,et al.Food-derived immunomodulatory peptides[J].Journal of the Science of Food and Agriculture,2016,96(11):3 631-3 641.
[14] XU Z,MAO T M,HUANG L,et al.Purification and identification immunomodulatory peptide from rice protein hydrolysates[J].Food and Agricultural Immunology,2019,30(1):150-162.
[15] 邓志程. 马氏珠母贝全脏器免疫活性肽的制备及其免疫活性的研究[D].广州:广东海洋大学,2015.
DENG Z C.Study on the preparation of Pinctada martensi immunomodulating peptide and its immunity function[D].Guangzhou:Guangdong Ocean University,2015.
[16] 石红岭. 林蛙油免疫活性肽的制备及体外活性研究[D].长春:吉林大学,2020.
SHI H L.Preparation and bioactivity of immunopeptide in vitro from oviductus ranae[D].Changchun:Jilin University,2020
[17] CIAN R E,LÓPEZ-POSADAS R,DRAGO S R,et al.A Porphyra columbina hydrolysate upregulates IL-10 production in rat macrophages and lymphocytes through an NF-κB,and p38 and JNK dependent mechanism[J].Food Chemistry,2012,134(4):1 982-1 990.
[18] HE P,WANG Q,ZHAN Q P,et al.Purification and characterization of immunomodulatory peptides from enzymatic hydrolysates of duck egg ovalbumin[J].Food & Function,2021,12(2):668-681.
[19] PARKER F,MIGLIORE-SAMOUR D,FLOCH F.et al.Immunostimulating hexapeptide from human casein:amino acid sequence,synthesis and biological properties[J].European Journal of Biochemistry,1984,145(3):677-682.
[20] FAJARDO-ESPINOZA F S,ORDAZ-PICHARDO C,SANKAR U,et al.In vitro cytomodulatory and immunomodulatory effects of bovine colostrum whey protein hydrolysates[J].International Journal of Food Science and Technology,2021,56(5):2 109-2 121.
[21] ACOSTA J,ROA F,GONZÁLEZ-CHAVARRÍA I,et al.In vitro immunomodulatory activities of peptides derived from Salmo salar NK-lysin and cathelicidin in fish cells[J].Fish & Shellfish Immunology,2019,88:587-594.
[22] LI Z Y,ZHAO S,XIN X D,et al.Purification and characterization of a novel immunomodulatory hexapeptide from alcalase hydrolysate of ultramicro-pretreated silkworm(Bombyx mori) pupa protein[J].Journal of Asia-Pacific Entomology,2019,22(3):633-637.
[23] FANG Y,PAN X,ZHAO E M,et al.Isolation and identification of immunomodulatory selenium-containing peptides from selenium-enriched rice protein hydrolysates[J].Food Chemistry,2019,275:696-702.
[24] WU W J,SUN C Z,WANG G,et al.Immunomodulatory activities of non-prolamin proteins in wheat germ and gluten[J].Journal of Cereal Science,2017,76:206-214.
[25] CRUZ-CHAMORRO I,ÁLVAREZ-SÁNCHEZ N,SANTOS-SÁNC-HEZ G,et al.Immunomodulatory and antioxidant properties of wheat gluten protein hydrolysates in human peripheral blood mononuclear cells[J].Nutrients,2020,12(6):1673.
[26] ASHAOLU T J,YANTIAM N,YUPANQUI C T.Immunomodulatory effects of pepsin-educed soy protein hydrolysate in rats and murine cells[J].Functional Foods in Health and Disease,2017,7(11):889-900.
[27] GAO Y,ZHANG X,REN G,et al.Peptides from extruded lupin(Lupinus albus L.) regulate inflammatory activity via the p38 MAPK signal transduction pathway in RAW 264.7 cells[J].Journal of Agricultural and Food Chemistry,2020,68(42):11 702-11 709.
[28] CRUZ-CHAMORRO I,ÁLVAREZ-SÁNCHEZ N,MILLÁN-LINARES M D C,et al.Lupine protein hydrolysates decrease the inflammatory response and improve the oxidative status in human peripheral lymphocytes[J].Food Research International(Ottawa,Ont.),2019,126:108585.
[29] CIAN R E,HERNÁNDEZ-CHIRLAQUE C,GÁMEZ-BELMONTE R,et al.Green Alga ulva spp.hydrolysates and their peptide fractions regulate cytokine production in splenic macrophages and lymphocytes involving the TLR4-NFκB/MAPK pathways[J].Marine drugs,2018,16(7):235.
[30] HAYES M.Food proteins and bioactive peptides:New and novel sources,characterisation strategies and applications[J].Foods,2018,7(3):38.
[31] WU W J,ZHANG M M,REN Y,et al.Characterization and immunomodulatory activity of a novel peptide,ECFSTA,from wheat germ globulin[J].Journal of Agricultural and Food Chemistry,2017,65(27):5 561-5 569.
[32] ZHANG Z W,HU X Y,LIN L,et al.Immunomodulatory activity of low molecular-weight peptides from Nibea japonica in RAW264.7 cells via NF-κB pathway[J].Marine Drugs,2019,17(7):404.
[33] ALVES T O,D’ALMEIDA C T S,SCHERF K A,et al.Modern approaches in the identification and quantification of immunogenic peptides in cereals by LC-MS/MS[J].Frontiers in Plant Science,2019,10:1470.
[34] TU M L,CHENG S Z,LU W H,et al.Advancement and prospects of bioinformatics analysis for studying bioactive peptides from food-derived protein:Sequence,structure,and functions[J].TrAC Trends in Analytical Chemistry,2018,105:7-17.
[35] MULLAISELVAN I,KANAGARAJ V,SEKAR S,et al.Studies on immunomodulatory effect of casein phospho peptide isolated from cultured dairy product[J].International Research Journal of Pure and Applied Chemistry,2020,21(23):28-40.
[36] ADAMS C,SAWH F,GREEN-JOHNSON J M,et al.Characterization of casein-derived peptide bioactivity:Differential effects on angiotensin-converting enzyme inhibition and cytokine and nitric oxide production[J].Journal of Dairy Science,2020,103(7):5 805-5 815.
[37] KIEWIET M B G,DEKKERS R,GROS M,et al.Toll-like receptor mediated activation is possibly involved in immunoregulating properties of cow’s milk hydrolysates[J].PLoS One,2017,12(6):e0178191.
[38] MERAM C,WU J P.Anti-inflammatory effects of egg yolk livetins(α,β,and γ-livetin) fraction and its enzymatic hydrolysates in lipopolysaccharide-induced RAW 264.7 macrophages[J].Food Research International(Ottawa,Ont.),2017,100(Pt 1):449-459.
[39] LEE J H,PAIK H D.Anticancer and immunomodulatory activity of egg proteins and peptides:A review[J].Poultry Science,2019,98(12):6 505-6 516.
[40] YU W L,FIELD C J,WU J P.Purification and identification of anti-inflammatory peptides from spent hen muscle proteins hydrolysate[J].Food Chemistry,2018,253:101-107.
[41] LI Q Q,WANG S K,POUNGCHAWANWONG S,et al.Effect of peptides from Alaska pollock on intestinal mucosal immunity function and purification of active fragments[J].Nutrients,2019,11(10):2 517.
[42] CAI J Y,LI X,WANG X,et al.A human β-casein-derived peptide BCCY-1 modulates the innate immune response[J].Food Chemistry,2021,348(30):129111.
[43] LI Z Y,ZHAO S,XIN X D,et al.Purification,identification and functional analysis of a novel immunomodulatory peptide from silkworm pupa protein[J].International Journal of Peptide Research and Therapeutics,2020,26(1):243-249.
[44] CAO H,CAO J F,ZHANG Y J,et al.Continuous preparation and characterization of immunomodulatory peptides from type II collagen by a novel immobilized enzyme membrane reactor with improved performance[J].Journal of Food Biochemistry,2019,43(7):e12862.
[45] 頡宇, 胡锦灵,赵宏飞,等.基于生物信息学定向制备柠条籽蛋白抗氧化肽的工艺优化[J].食品科学,2020,41(20):278-284.
JIE Y,HU J L,ZHAO H F,et al.Optimization of bioinformatics-based directional preparation of antioxidant peptide from Caragana seed protein[J].Shipin Kexue/Food Science,2020,41(20):278-284.
[46] KE,SKA P,WÓJCIAK K M,STADNIK J.Bioactive peptides from beef products fermented by acid whey-in vitro and in silico study[J].Scientia Agricola,2019,76(4):311-320.