[1] WANG S H,HUANG C Y,CHEN C Y,et al.Isolation and purification of brown algae fucoidan from Sargassum siliquosum and the analysis of anti-lipogenesis activity[J].Biochemical Engineering Journal,2021,165:107798.
[2] WANG Y,XING M C,CAO Q,et al.Biological activities of fucoidan and the factors mediating its therapeutic effects:A review of recent studies[J].Marine Drugs,2019,17(3):183.
[3] YIN J Y,YANG X Q,XIA B,et al.The fucoidan from sea cucumber Apostichopus japonicus attenuates lipopolysaccharide-challenged liver injury in C57BL/6 J mice[J].Journal of Functional Foods,2019,61:103493.
[4] PRADHAN B,PATRA S,NAYAK R,et al.Multifunctional role of fucoidan,sulfated polysaccharides in human health and disease:A journey under the sea in pursuit of potent therapeutic agents[J].International Journal of Biological Macromolecules,2020,164:4 263-4 278.
[5] GAO W J,GUO Y Y,WANG L Z,et al.Ameliorative and protective effects of fucoidan and sodium alginate against lead-induced oxidative stress in Sprague Dawley rats[J].International Journal of Biological Macromolecules,2020,158:662-669.
[6] MANSOUR M B,BALTI R,YACOUBI L,et al.Primary structure and anticoagulant activity of fucoidan from the sea cucumber Holothuria polii[J].International Journal of Biological Macromolecules,2019,121:1 145-1 153.
[7] CHUNG C H,LU K Y,LEE W C,et al.Fucoidan-based,tumor-activated nanoplatform for overcoming hypoxia and enhancing photodynamic therapy and antitumor immunity[J].Biomaterials,2020,257:120227.
[8] SANJEEWA K K A,JAYAWARDENA T U,KIM S Y,et al.Fucoidan isolated from invasive Sargassum horneri inhibit LPS-induced inflammation via blocking NF-κB and MAPK pathways[J].Algal Research,2019,41:101561.
[9] ZHAO X,GUO F,HU J,et al.Antithrombotic activity of oral administered low molecular weight fucoidan from Laminaria japonica[J].Thrombosis Research,2016,144:46-52.
[10] FLÓREZ-FERNÁNDEZ N,TORRES M D,GONZÁLEZ-MUÑOZ M J,et al.Potential of intensification techniques for the extraction and depolymerization of fucoidan[J].Algal Research,2018,30:128-148.
[11] SILCHENKO A S,RASIN A B,KUSAYKIN M I,et al.Modification of native fucoidan from Fucus evanescens by recombinant fucoidanase from marine bacteria Formosa algae[J].Carbohydrate Polymers,2018,193:189-195.
[12] 王莹.岩藻聚糖硫酸酯酶产生菌的筛选,酶学性质研究及酶解产物抗氧化活性预测系统的建立[D].青岛:中国海洋大学,2013.
WANG Y.Screening of fucoindanase-producing bacteria,fucoindanase characterization,and establishment of the hydrolyzate antioxidant activity predication system[D].Qingdao:Ocean University of China.2013.
[13] BELIK A A,TABAKMAKHER K M,SILCHENKO A S,et al.Sulfated steroids of Halichondriidae family sponges-Natural inhibitors of polysaccharide-degrading enzymes of bacterium Formosa algae,inhabiting brown alga Fucus evanescens[J].Carbohydrate Research,2019,484:107776.
[14] VAN VLIET D M,PALAKAWONG NA AYUDTHAYA S,DIOP S,et al.Anaerobic degradation of sulfated polysaccharides by two novel Kiritimatiellales strains isolated from black sea sediment[J].Frontiers in Microbiology,2019,10:253.
[15] DESCAMPS V,COLIN S,LAHAYE M,et al.Isolation and culture of a marine bacterium degrading the sulfated fucans from marine brown algae[J].Marine Biotechnology,2006,8(1):27-39.
[16] THANASSI N M,NAKADA H I.Enzymic degradation of fucoidan by enzymes from the hepatopancreas of abalone,Haliotus species[J].Archives of Biochemistry and Biophysics,1967,118(1):172-177.
[17] TANAKA K,SORAI S.Hydrolysis of fucoidan by abalone liver alpha-L-fucosidase[J].FEBS Letters,1970,9(1):45-48.
[18] SICHERT A,CORZETT C H,SCHECHTER M S,et al.Verrucomicrobia use hundreds of enzymes to digest the algal polysaccharide fucoidan[J].Nature Microbiology,2020,5(8):1 026-1 039.
[19] KIM W J,KIM S M,LEE Y H,et al.Isolation and characterization of marine bacterial strain degrading fucoidan from Korean Undaria pinnatifida Sporophylls[J].Journal of Microbiology and Biotechnology,2008,18(4):616-623.
[20] KIM W J,PARK J W,PARK J K,et al.Purification and characterization of a fucoidanase(FNase S) from a marine bacterium Sphingomonas paucimobilis PF-1[J].Marine Drugs,2015,13(7):4 398-4 417.
[21] OHSHIRO T,OHMOTO Y,ONO Y,et al.Isolation and characterization of a novel fucoidan-degrading microorganism[J].Bioscience,Biotechnology,and Biochemistry,2010,74(8):1 729-1 732.
[22] IVANOVA E P,SAWABE T,ALEXEEVA Y V,et al. Pseudoalteromonas issachenkonii sp.nov.,a bacterium that degrades the thallus of the brown alga Fucus evanescens[J].International Journal of Systematic and Evolutionary Microbiology,2002,52(1):229-234.
[23] 张袁, 吴茜茜,王杏文,等.岩藻多糖酶产生菌的筛选,鉴定及发酵条件初探[J].包装与食品机械,2010,28(3):32-35;45.
ZAHNG Y,WU Q Q,WANG X W,et al.Screeniing,identification and fermentation of fucoidanase producing strains[J].Packaging and Food Machinery,2010,28(3):32-35;45.
[24] 吴克, 刘斌,吴茜茜,等.海洋真菌 Dendryphiella arenaria TM94 产岩藻多糖酶发酵及酶学性质[J].生物学杂志,2003,20(2):14-16.
WU K,LIU B,WU Q Q,et al.Fermentation of fucoidanase production by marine fungus Dedry arenaria and enzyme properties[J].Journal of Biology,2003,20(2):14-16.
[25] 吴茜茜, 吴克,张洁,等.海洋真菌 Fusarium sp.LD8 岩藻多糖酶的液态发酵条件研究[J].菌物学报,2006,25(1):77-82.
WU Q Q,WU K,ZHANG J,et al.Liguid state fermentation of fucoidanase from marine fungi Fusarium sp.LD8[J].Mycosystema,2006,25(1):77-82.
[26] RODRÍGUEZ-JASSO R M,MUSSATTO S I,SEPU′LVEDA L,et al.Fungal fucoidanase production by solid-state fermentation in a rotating drum bioreactor using algal biomass as substrate[J].Food and Bioproducts Processing,2013,91(4):587-594.
[27] SILCHENKO A S,KUSAYKIN M I,ZAKHARENKO A M,et al.Endo-1,4-fucoidanase from Vietnamese marine mollusk Lambis sp.which producing sulphated fucooligosaccharides[J].Journal of Molecular Catalysis B:Enzymatic,2014,102:154-160.
[28] 常耀光. 海参岩藻聚糖硫酸酯及其酶解产物的制备,结构与活性研究[D].青岛:中国海洋大学,2010.
CHANG Y G.Study on the producing,sturcuture and activity of sea cucumber fucoidan and its enzymatic degradation products[D].Qingdao:Ocean University of China,2010.
[29] KUSAYKIN M I,BURTSEVA Y V,SVETASHEVA T G,et al.Distribution of O-glycosylhydrolases in marine invertebrates.Enzymes of the marine mollusk Littorina kurila that catalyze fucoidan transformation[J].Biochemistry(Moscow),2003,68(3):317-324.
[30] WU Q Q,MA S,XIAO H R,et al.Purification and the secondary structure of fucoidanase from Fusarium sp.LD8[J].Evidence-Based Complementary and Alternative Medicine,2011,2011:196190.
[31] SAKAI T,KIMURA H,KOJIMA K,et al.Marine bacterial sulfated fucoglucuronomannan(SFGM) lyase digests brown algal SFGM into trisaccharides[J].Marine Biotechnology,2003,5(1):70-78.
[32] 霍立华.岩藻聚糖硫酸酯酶产生菌筛选和酶学性质的研究以及岩藻寡糖的应用研究[D].青岛:中国海洋大学,2003.
HUO L H.Screening of fucoidanase sulfate producing bacteria and study on its enzyme characters and the application of fucoidan oligosaccharides[D].Qingdao:Ocean University of China,2003.
[33] 王春霞. 海参岩藻聚糖硫酸酯酶产生菌的筛选鉴定,发酵条件优化及酶学性质研究[D].青岛:中国海洋大学,2011.
WANG C X.Screening and identifying of a fucoidan-degrading marine bacterial strain, optimization of enzyme production condition, and characterization of the fucoidanase[D].Qingdao:Ocean University of China,2011.
[34] 王莹, 李八方,赵雪.产岩藻聚糖硫酸酯酶微生物的筛选及产酶条件优化[J].中国食品学报,2013,13(5):100-105.
WANG Y,LI B F,ZHAO X.Screening of fucoidanase-producing microorganisms and optimization of condition for fucoidanase production[J].Journal of Chinese Institute of Food Science and Technology,2013,13(5):100-105.
[35] 张翠玉, 薛长湖,于龙,等.基于 pHBH 法的岩藻聚糖硫酸酯酶酶活测定方法[J].中国食品学报,2013,13(7):200-206.
ZHANG C Y,XUE C H,YU L,et al.Fucoidanase activity determination method on basis of pHBH method[J].Journal of Chinese Institute of Food Science and Technology,2013,13(7):200-206.
[36] 姜琪, 谌素华,郑琼仪,等.可控酶降解马尾藻岩藻聚糖硫酸酯的研究[J].农产品加工(上),2015(7):5-7;11.
JING Q,CHEN S H,ZHENG Q Y,et al.Enzyme-catalyzed controllable degradation of Sargassum fucoidan[J].Farm Products Processing,2015(7):5-7;11.
[37] SILCHENKO A S,KUSAYKIN M I,KURILENKO V V,et al.Hydrolysis of fucoidan by fucoidanase isolated from the marine bacterium,Formosa algae[J].Marine Drugs,2013,11(7):2 413-2 430.
[38] TAKAYAMA M,KOYAMA N,SAKAI T,et al.Enzymes capable of degrading a sulfated-fucose-containing polysaccharide and their encoding genes:US6489155[P].2002-12-03.
[39] COLIN S,DENIAUD E,JAM M,et al.Cloning and biochemical characterization of the fucanase FcnA:Definition of a novel glycoside hydrolase family specific for sulfated fucans[J].Glycobiology,2006,16(11):1 021-1 032.
[40] SILCHENKO A S,RASIN A B,KUSAYKIN M I,et al.Structure,enzymatic transformation,anticancer activity of fucoidan and sulphated fucooligosaccharides from Sargassum horneri[J].Carbohydrate Polymers,2017,175:654-660.
[41] ZUEVA A O,SILCHENKO A S,RASIN A B,et al.Expression and biochemical characterization of two recombinant fucoidanases from the marine bacterium Wenyingzhuangia fucanilytica CZ1127T[J].International Journal of Biological Macromolecules,2020,164:3 025-3 037.
[42] YU L,GE L,XUE C H,et al.Structural study of fucoidan from sea cucumber Acaudina molpadioides:A fucoidan containing novel tetrafucose repeating unit[J].Food Chemistry,2014,142:197-200.
[43] CHEN S G,HU Y Q,YE X Q,et al.Sequence determination and anticoagulant and antithrombotic activities of a novel sulfated fucan isolated from the sea cucumber Isostichopus badionotus[J].Biochimica et Biophysica Acta(BBA)-General Subjects,2012,1820(7):989-1 000.
[44] LI C,NIU Q F,LI S J,et al.Fucoidan from sea cucumber Holothuria polii:Structural elucidation and stimulation of hematopoietic activity[J].International Journal of Biological Macromolecules,2020,154:1 123-1 131.
[45] SAKAI T,ISHIZUKA K,SHIMANAKA K,et al.Structures of oligosaccharides derived from Cladosiphon okamuranus fucoidan by digestion with marine bacterial enzymes[J].Marine Biotechnology,2003,5(6):536-544.
[46] CHEVOLOT L,MULLOY B,RATISKOL J,et al.A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae[J].Carbohydrate Research,2001,330(4):529-535.
[47] HIFNEY A F,FAWZY M A,ABDEL-GAWAD K M,et al.Upgrading the antioxidant properties of fucoidan and alginate from Cystoseira trinodis by fungal fermentation or enzymatic pretreatment of the seaweed biomass[J].Food Chemistry,2018,269:387-395.
[48] RASIN A B,SILCHENKO A S,KUSAYKIN M I,et al.Enzymatic transformation and anti-tumor activity of Sargassum horneri fucoidan[J].Carbohydrate Polymers,2020,246:116635.
[49] CHEN Q R,KOU L Y,WANG F W,et al.Size-dependent whitening activity of enzyme-degraded fucoidan from Laminaria japonica[J].Carbohydrate Polymers,2019,225:115211.
[50] KUZNETSOVA T A,SMOLINA T P,BESEDNOVA N N,et al.Effect of sulfated polysaccharides from brown alga Fucus evanescens and their enzymatic transformation product on functional activity of innate immunity Cells[J].Antibiot Khimioter,2016,61(7-8):10-14.