[1] MERGA Y, CAMPBELL B J, RHODES J M.Mucosal barrier, bacteria and inflammatory bowel disease:Possibilities for therapy[J].Digestive Diseases (Basel, Switzerland), 2014, 32(4):475-483.
[2] VANCAMELBEKE M, VERMEIRE S.The intestinal barrier:A fundamental role in health and disease[J].Expert Review of Gastroenterology & Hepatology, 2017, 11(9):821-834.
[3] BERMÚDEZ-HUMARÁN L G, SALINAS E, ORTIZ G G, et al.From probiotics to psychobiotics:Live beneficial bacteria which act on the brain-gut axis[J].Nutrients, 2019, 11(4):890.
[4] KOZAKOVA H, SCHWARZER M, TUCKOVA L, et al.Colonization of germ-free mice with a mixture of three Lactobacillus strains enhances the integrity of gut mucosa and ameliorates allergic sensitization[J].Cellular & Molecular Immunology, 2016, 13(2):251-262.
[5] LI X, WANG N, YIN B, et al.Effects of Lactobacillus plantarum CCFM0236 on hyperglycaemia and insulin resistance in high-fat and streptozotocin-induced type 2 diabetic mice[J].Journal of Applied Microbiology, 2016, 121(6):1 727-1 736.
[6] MAYNARD C L, ELSON C O, HATTON R D, et al.Reciprocal interactions of the intestinal microbiota and immune system[J].Nature, 2012, 489(7415):231-241.
[7] REN Z H, GUO C Y, YU S M, et al.Progress in mycotoxins affecting intestinal mucosal barrier function[J].International Journal of Molecular Sciences, 2019, 20(11):2777.
[8] GÜNTHER C, JOSENHANS C, WEHKAMP J.Crosstalk between microbiota, pathogens and the innate immune responses[J].International Journal of Medical Microbiology, 2016, 306(5):257-265.
[9] HONDA K, LITTMAN D R.The microbiota in adaptive immune homeostasis and disease[J].Nature, 2016, 535(7610):75-84.
[10] HOU Q H, YE L L, LIU H F, et al.Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22[J].Cell Death and Differentiation, 2018, 25(9):1 657-1 670.
[11] WU H Q, XIE S, MIAO J F, et al.Lactobacillus reuteri maintains intestinal epithelial regeneration and repairs damaged intestinal mucosa[J].Gut Microbes, 2020, 11(4):997-1 014.
[12] YI H B, WANG L, XIONG Y X, et al.Effects of Lactobacillus reuteri LR1 on the growth performance, intestinal morphology, and intestinal barrier function in weaned pigs[J].Journal of Animal Science, 2018, 96(6):2 342-2 351.
[13] CUI Y J, LIU L, DOU X X, et al.Lactobacillus reuteri ZJ617 maintains intestinal integrity via regulating tight junction, autophagy and apoptosis in mice challenged with lipopolysaccharide[J].Oncotarget, 2017, 8(44):77 489-77 499.
[14] CHEN L F, LI H Y, LI J Y, et al.Lactobacillus rhamnosus GG treatment improves intestinal permeability and modulates microbiota dysbiosis in an experimental model of sepsis[J].International Journal of Molecular Medicine, 2019, 43(3):1 139-1 148.
[15] REN C C, DOKTER-FOKKENS J, FIGUEROA LOZANO S, et al.Lactic acid bacteria may impact intestinal barrier function by modulating goblet cells[J].Molecular Nutrition & Food Research, 2018, 62(6):1700572.
[16] MARTÍN R, CHAMIGNON C, MHEDBI-HAJRI N, et al.The potential probiotic Lactobacillus rhamnosus CNCM I-3690 strain protects the intestinal barrier by stimulating both mucus production and cytoprotective response[J].Scientific Reports, 2019, 9:5398.
[17] PAPARO L, AITORO R, NOCERINO R, et al.Direct effects of fermented cow’s milk product with Lactobacillus paracasei CBAL74 on human enterocytes[J].Beneficial Microbes, 2018, 9(1):165-171.
[18] ROKANA N, SINGH R, MALLAPPA R H, et al.Modulation of intestinal barrier function to ameliorate Salmonella infection in mice by oral administration of fermented milks produced with Lactobacillus plantarum MTCC 5690:A probiotic strain of Indian gut origin[J].Journal of Medical Microbiology, 2016, 65(12):1 482-1 493.
[19] CHENG F S, PAN D, CHANG B, et al.Probiotic mixture VSL#3:An overview of basic and clinical studies in chronic diseases[J].World Journal of Clinical Cases, 2020, 8(8):1 361-1 384.
[20] LEBEER S, BRON P A, MARCO M L, et al.Identification of probiotic effector molecules:Present state and future perspectives[J].Current Opinion in Biotechnology, 2018, 49:217-223.
[21] JOHNSON-HENRY K C, HAGEN K E, GORDONPOUR M, et al.Surface-layer protein extracts from Lactobacillus helveticus inhibit enterohaemorrhagic Escherichia coli O157:H7 adhesion to epithelial cells[J].Cellular Microbiology, 2007, 9(2):356-367.
[22] KIM S Y, SHIN K S, LEE H.Determination of primary factors with adhesive property of Lactobacillus brevis FSB-1 to rat colonic mucin[J].Food Science and Biotechnology, 2010, 19(5):1 317-1 323.
[23] WOO V, ALENGHAT T.Host-microbiota interactions:Epigenomic regulation[J].Current Opinion in Immunology, 2017, 44:52-60.
[24] WEI Z T, CUI Y Q, TIAN L, et al.Probiotic Lactiplantibacillus plantarum N-1 could prevent ethylene glycol-induced kidney stones by regulating gut microbiota and enhancing intestinal barrier function[J].The FASEB Journal, 2021, 35(11):e21937.
[25] YANG B, LI M J, WANG S, et al.Lactobacillus ruminis alleviates DSS-induced colitis by inflammatory cytokines and gut microbiota modulation[J].Foods (Basel, Switzerland), 2021, 10(6):1349.
[26] KIM S H, JEUNG W, CHOI I D, et al.Lactic acid bacteria improves Peyer’s patch cell-mediated immunoglobulin A and tight-junction expression in a destructed gut microbial environment[J].Journal of Microbiology and Biotechnology, 2016, 26(6):1 035-1 045.
[27] BJARNASON I, SISSION G, HAYEE B.A randomised, double-blind, placebo-controlled trial of a multi-strain probiotic in patients with asymptomatic ulcerative colitis and Crohn’s disease[J].Inflammopharmacology, 2019, 27(3):465-473.
[28] COSTA R F A, FERRARI M L A, BRINGER M A, et al.Characterization of mucosa-associated Escherichia coli strains isolated from Crohn’s disease patients in Brazil[J].BMC Microbiology, 2020, 20(1):178.
[29] ZAKERSKA-BANASZAK O, TOMCZAK H, GABRYEL M, et al.Dysbiosis of gut microbiota in Polish patients with ulcerative colitis:A pilot study[J].Scientific Reports, 2021, 11:2166.
[30] MOLSKA M, REGUŁA J.Potential mechanisms of probiotics action in the prevention and treatment of colorectal cancer[J].Nutrients, 2019, 11(10):2453.
[31] LIU Z, QIN H, YANG Z, et al.Randomised clinical trial:The effects of perioperative probiotic treatment on barrier function and post-operative infectious complications in colorectal cancer surgery- a double-blind study[J].Alimentary Pharmacology & Therapeutics, 2011, 33(1):50-63.
[32] SHOUKAT S.Potential anti-carcinogenic effect of probiotic and lactic acid bacteria in detoxification of benzo a pyrene:A review[J].Trends in Food Science & Technology, 2020, 99:450-459.
[33] LANDY J, RONDE E, ENGLISH N, et al.Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer[J].World Journal of Gastroenterology, 2016, 22(11):3 117-3 126.
[34] MARKOWIAK-KOPEĆ P, ŚLIŻEWSKA K.The effect of probiotics on the production of short-chain fatty acids by human intestinal microbiome[J].Nutrients, 2020, 12(4):1107.
[35] ELAMIN E E, MASCLEE A A, DEKKER J, et al.Short-chain fatty acids activate AMP-activated protein kinase and ameliorate ethanol-induced intestinal barrier dysfunction in caco-2 cell monolayers[J].The Journal of Nutrition, 2013, 143(12):1 872-1 881.
[36] PAPALIAGKAS V, ANOGIANAKI A, ANOGIANAKIS G, et al.The proteins and the mechanisms of apoptosis:A mini-review of the fundamentals[J].Hippokratia, 2007, 11(3):108-113.
[37] RABIEI M, ZARRINI G, MAHDAVI M.Lactobacillus casei UT1 isolated from northwest of Iran traditional curd exerts anti-proliferative and apoptosis inducing effects in human colorectal tumor HCT 116 cells[J].Advanced Pharmaceutical Bulletin, 2020, 10(1):125-129.
[38] SUN M Y, LIU W W, SONG Y L, et al.The effects of Lactobacillus plantarum-12 crude exopolysaccharides on the cell proliferation and apoptosis of human colon cancer (HT-29) cells[J].Probiotics and Antimicrobial Proteins, 2021, 13(2):413-421.
[39] LIU E, LEE H S, ARONSSON C A, et al.Risk of pediatric celiac disease according to HLA haplotype and country[J].The New England Journal of Medicine, 2014, 371(1):42-49.
[40] WITHOFF S, LI Y, JONKERS I, et al.Understanding celiac disease by genomics[J].Trends in Genetics, 2016, 32(5):295-308.
[41] VERDU E F, GALIPEAU H J, JABRI B.Novel players in coeliac disease pathogenesis:Role of the gut microbiota[J].Nature Reviews Gastroenterology & Hepatology, 2015, 12(9):497-506.
[42] OLIVARES M, NEEF A, CASTILLEJO G, et al.The HLA-DQ2 genotype selects for early intestinal microbiota composition in infants at high risk of developing coeliac disease[J].Gut, 2015, 64(3):406-417.
[43] BASCUÑÁN K A, ARAYA M, RONCORONI L, et al.Dietary gluten as a conditioning factor of the gut microbiota in celiac disease[J].Advances in Nutrition, 2019, 11(1):160-174.
[44] CAMINERO A, MCCARVILLE J L, GALIPEAU H J, et al.Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2[J].Nature Communications, 2019, 10:1198.
[45] CAMINERO A, GALIPEAU H J, MCCARVILLE J L, et al.Duodenal bacteria from patients with celiac disease and healthy subjects distinctly affect gluten breakdown and immunogenicity[J].Gastroenterology, 2016, 151(4):670-683.
[46] LAMMERS K M, LU R L, BROWNLEY J, et al.Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3[J].Gastroenterology, 2008, 135(1):194-204.
[47] MEDINA M, DE PALMA G, RIBES-KONINCKX C, et al.Bifidobacterium strains suppress in vitro the pro-inflammatory milieu triggered by the large intestinal microbiota of coeliac patients[J].Journal of Inflammation (London, England), 2008, 5:19.
[48] XU Q, LI X F, WANG E Y, et al.A cellular model for screening of lactobacilli that can enhance tight junctions[J].RSC Advances, 2016, 6(113):111 812-111 821.
[49] WANG G, XU Q, JIN X, et al.Effects of lactobacilli with different regulatory behaviours on tight junctions in mice with dextran sodium sulphate-induced colitis[J].Journal of Functional Foods, 2018, 47:107-115.