In this study, a rat model of gastric motility disorders was used to study the ameliorating effects of five medicinal and edible homologous plants, including chicory, tangerine peel, chicken gizzards, hawthorn, and Phyllanthus emblica. The gastric emptying rate, gastric acid, protease, gastric juice, serum ghrelin, gastrin, tyrosinase receptor gene (c-kit) and stem cell factor were measured, and the antral tissue sections were observed. Chicory, hawthorn, and P. emblica significantly increased the gastric emptying rate (P<0.05). Chicory and tangerine peel significantly decreased the activity and excretion rate of gastric free acid (P<0.05). Hawthorn significantly increased the activity and excretion of pepsin (P<0.05). Chicken gizzards significantly increased the pepsin excretion rate and gastric fluid volume (P<0.05). In addition, chicory and hawthorn significantly increased the content of serum ghrelin (P<0.05), and P. emblica significantly increased the content of serum gastrin (P<0.05). Chicory can repair the gastric fundic gland layer and significantly up-regulate the transcription level of c-kit. In conclusion, chicory, hawthorn, and P. emblica could promote gastric motility and have the potential to be developed into pro-digestive foods.
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