综述与专题评论

天然柑橘香豆素的分布、提取分析及生物活性研究进展

  • 王群娣 ,
  • 赵晨露 ,
  • 王旭婷 ,
  • 程玉娇 ,
  • 韩冷 ,
  • 龙兴瑶 ,
  • 余波 ,
  • 刘君 ,
  • 李贵节
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  • 1(西南大学柑桔研究所,重庆,400712)
    2(国家柑桔工程技术研究中心,重庆,400712)
    3(农业农村部柑橘类果品质量安全控制重点实验室,重庆,400712)
    4(重庆市第二师范学院儿童营养与健康发展协同创新中心,重庆,400067)
    5(四川省丹橙现代果业有限公司,四川 眉山,620299)
    6(河南华测检测技术有限公司,河南 郑州,450001)
第一作者:硕士研究生(李贵节副研究员和龙兴瑶研究员为共同通信作者,E-mail:liguijie@cric.cn;longxy@cque.edu.com)

收稿日期: 2023-11-15

  修回日期: 2024-01-08

  网络出版日期: 2024-06-11

基金资助

重庆市自然科学基金面上项目(CSTB2023NSCQ-MSX0282);国家自然科学基金青年基金项目(32101891);西南大学中央高校基本科研业务费项目(SWU-KR22050);重庆市自然科学基金博士后科学基金项目(cstc2021jcyj-bshX0043);西南大学国内合作项目(2023001206)

Research progress on distribution, extraction and analysis, and biological activity of natural citrus coumarins

  • WANG Qundi ,
  • ZHAO Chenlu ,
  • WANG Xuting ,
  • CHENG Yujiao ,
  • HAN Leng ,
  • LONG Xingyao ,
  • YU Bo ,
  • LIU Jun ,
  • LI Guijie
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  • 1(Citrus Research Institute, Southwest University, Chongqing 400712, China)
    2(National Citrus Engineering Research Center, Chongqing 400712, China)
    3(Key Laboratory of Quality and Safety Control of Citrus Fruits, Ministry of Agriculture and Rural Affairs, Chongqing 400712, China)
    4(Collaborative Innovation Center for Child Nutrition and Health Development, Chongqing 400067, China)
    5(Sichuan Dancheng Modern Fruit Industry Co.Ltd., Meishan 620299, China)
    6(Henan Centre Testing International Group Co.Ltd., Zhengzhou 450001, China)

Received date: 2023-11-15

  Revised date: 2024-01-08

  Online published: 2024-06-11

摘要

柑橘包含柑橘属及其近缘植物,常见品种有甜橙、宽皮橘、柚子、柠檬和杂柑等,其果实是全球产量最高、经济体量最大的水果,也是重要的药食同源植物和天然产物宝库。柑橘香豆素类化合物是一大类具有苯并α-吡喃酮结构的次生代谢产物,在植物应对环境胁迫、抵御病虫侵袭等过程中发挥重要作用。大量研究显示柑橘香豆素还对人体和哺乳动物具有多种生物学活性,如抗炎、抗癌、抗病毒以及保护心脑血管、神经和消化系统等作用。随着后疫情时代对药食同源关注度不断提升及大健康产业的加速发展,柑橘精深加工势头强劲,针对其香豆素等天然活性产品的开发利用极具市场潜力。该文综述了天然柑橘香豆素的研究进展,重点就其结构和分布、提取和分析方法以及功能活性作归纳和梳理,旨在为基于结构和活性的柑橘香豆素研究及其精深加工产品开发提供参考。

本文引用格式

王群娣 , 赵晨露 , 王旭婷 , 程玉娇 , 韩冷 , 龙兴瑶 , 余波 , 刘君 , 李贵节 . 天然柑橘香豆素的分布、提取分析及生物活性研究进展[J]. 食品与发酵工业, 2024 , 50(8) : 343 -355 . DOI: 10.13995/j.cnki.11-1802/ts.037958

Abstract

Citrus comprises the Citrus genus and its closely related plants of which common varieties include sweet orange, mandarin, pomelo, lemon and their hybrids.Citrus fruits are among the highest-yield and most economically valuable fruits in the world.They also serve as important medicinal and edible homologous plants and repositories of natural products.Citrus coumarins, characterized by a benzo-α-pyrone structure, form a large class of secondary metabolites which play an important role in plant response to environmental stress and defense against pests and diseases.In addition, numerous studies indicate that citrus coumarins exhibit diverse biological activities in humans or mammals, such as anti-inflammatory, anticancer and antiviral activities, and protective effects on cerebral and cardiovascular, nervous, and digestive systems.With the increasing post-pandemic focus on medicinal and dietary sources and the accelerated development of the big health industry, there is a robust momentum in the deep processing of citrus.This trend particularly underscores the market potential for the development and utilization of natural active products such as coumarins derived from citrus.This article provided a comprehensive review of the research progress on natural citrus coumarins, focusing on their structure and distribution, extraction and analytical methods, as well as functional activities.The aim is to offer insights and guidance for research on citrus coumarins based on structure and activity, as well as the development of deeply processed products.

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