综述与专题评论

人参皂苷CK的规模化制备及生物活性研究进展

  • 曹静怡 ,
  • 曹园 ,
  • 张佳汝 ,
  • 周杨佳兰 ,
  • 郭珍妮 ,
  • 邵娟娟
展开
  • (河北农业大学 理工系,河北 沧州,061000)
第一作者:本科生(邵娟娟副教授为通信作者,E-mail:386953141@qq.com)

收稿日期: 2024-05-14

  修回日期: 2024-06-24

  网络出版日期: 2025-03-28

基金资助

河北农业大学2024年大学生创新创业训练计划基金项目(2024005)

Research progress on large-scale preparation and biological activity of ginsenoside CK

  • CAO Jingyi ,
  • CAO Yuan ,
  • ZHANG Jiaru ,
  • ZHOU Yangjialan ,
  • GUO Zhenni ,
  • SHAO Juanjuan
Expand
  • (College of Science and Technology, Agricultural University of Hebei, Cangzhou 061000, China)

Received date: 2024-05-14

  Revised date: 2024-06-24

  Online published: 2025-03-28

摘要

人参是一种名贵的中药材,稀有人参皂苷是人参最有效的功能成分,通过生物转化方法制备稀有人参皂苷已成为当下研究热点。人参皂苷Compound K(人参皂苷 CK)具有抗肿瘤、抗炎症、延缓皮肤衰老、抗糖尿病及其并发症、抗抑郁、抗骨质疏松症等生物活性。该文结合国内外相关研究,系统综述了适合大规模制备人参皂苷CK的方法及其生物活性,以期为人参皂苷CK的大批量生产及进一步探索其药理机制提供参考意见。

本文引用格式

曹静怡 , 曹园 , 张佳汝 , 周杨佳兰 , 郭珍妮 , 邵娟娟 . 人参皂苷CK的规模化制备及生物活性研究进展[J]. 食品与发酵工业, 2025 , 51(5) : 371 -379 . DOI: 10.13995/j.cnki.11-1802/ts.039872

Abstract

Ginseng is a valuable Chinese herbal medicine, and rare ginsenosides are the most effective functional components in ginseng.The preparation of rare ginsenosides by biotransformation has become a research hotspot.Ginsenoside compound K (ginsenoside CK) has the capacity to be anti-tumor, anti-inflammatory, anti-aging skin, anti-diabetes, anti-depression, and anti-osteoporosis agents, while maintains other beneficial biological properties.In this paper, the methods suitable for large-scale preparation of ginsenoside CK and its biological activity were systematically reviewed to provide reference for the massive production of ginsenoside CK and further exploration of its pharmacological mechanism.

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