食品与发酵工业 >

2025 , Vol. 51 >Issue 21: 420 - 434

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.043257

综述与专题评论

生姜的抗炎活性成分、作用机制及其应用研究进展

  • 何福林 ,
  • 孙心雨 ,
  • 唐盛梅 ,
  • 邵金华 ,
  • 蒋黎艳
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  • 1(湖南科技学院 化学与生物工程学院,湖南 永州,425199)
    2(湘南优势植物资源综合利用湖南省重点实验室,湖南 永州,425199)
第一作者：硕士,教授(蒋黎艳副教授和邵金华教授为共同通信作者,E-mail:lyj5423@163.com;jinhua0212@163.com)

收稿日期: 2025-05-12

  修回日期: 2025-06-10

  网络出版日期: 2025-11-21

基金资助

湖南省自然科学基金项目(2024JJ7192);湖南省教育厅科学研究项目(24C0472);永州市指导性科技计划项目(2023YZ022)

收起

Research progress on the anti-inflammatory active components, mechanism of action, and applications of ginger (Zingiber officinale Roscoe)

  • HE Fulin ,
  • SUN Xinyu ,
  • TANG Shengmei ,
  • SHAO Jinhua ,
  • JIANG Liyan
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  • 1(College of Chemistry and Bioengineering, Hunan University of Science and Engineering, Yongzhou 425199,China)
    2(Key Laboratory of Comprehensive Utilization of Advantage Plants Resources in Hunan South,Yongzhou 425199,China)

Received date: 2025-05-12

  Revised date: 2025-06-10

  Online published: 2025-11-21

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摘要

生姜,一种药食同源的姜科植物,因其富含多种活性成分,在抗炎领域展现出了显著地潜力。生姜的抗炎活性成分主要包括姜辣素类、黄酮类化合物、生姜挥发油以及生姜多糖等,它们通过调控炎症介质的分泌、干预炎症信号通路的活化、调节免疫系统细胞的功能以及改善肠道菌群等机制,发挥抗炎作用。尽管生姜的抗炎作用已受到广泛关注,但目前关于其抗炎活性成分的研究较为分散,各成分之间的协同作用机制尚未完全阐明,抗炎机制的研究仍缺乏系统性和深度。基于此,该文重点综述了生姜的抗炎活性成分及其作用机制,并归纳了其在关节炎、溃疡性结肠炎、呼吸道炎症、心血管炎症等疾病中的应用,以期为生姜在抗炎领域的综合开发与转化应用提供参考。

关键词： 生姜; 活性成分; 抗炎机制; 炎症疾病

本文引用格式

何福林 , 孙心雨 , 唐盛梅 , 邵金华 , 蒋黎艳 . 生姜的抗炎活性成分、作用机制及其应用研究进展[J]. 食品与发酵工业, 2025 , 51(21) : 420 -434 . DOI: 10.13995/j.cnki.11-1802/ts.043257

Abstract

Ginger (Zingiber officinale Roscoe), a medicine and food homology plant from the ginger family, has garnered significant attention for its anti-inflammatory potential, largely due to its rich content of active components.The anti-inflammatory active ingredients in ginger mainly include gingerols, flavonoids, ginger volatile oil, and ginger polysaccharides.They exert anti-inflammatory effects through mechanisms such as modulating the secretion of inflammatory mediators, intervening in the activation of inflammatory signaling pathways, modulating immune cell functions, and improving intestinal flora.Despite the widespread recognition of its anti-inflammatory effects, research on active components of ginger remains fragmented.The synergistic mechanisms among these components have not been fully elucidated, and the study of anti-inflammatory mechanisms lacks systematic depth.Therefore, this review focuses on an overview of the anti-inflammatory active components of ginger and their mechanisms of action, and summarizes the applications of ginger and its active ingredients in arthritis, ulcerative colitis, respiratory inflammation, and cardiovascular inflammation.The aim is to provide a theoretical basis for the comprehensive development and translational application of ginger in the anti-inflammatory field.

Key words： ginger; active components; anti-inflammatory mechanisms; inflammatory diseases

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