该研究旨在优化薄荷醇乳液的稳定性和负载性能,采用壳聚糖与肉桂醛作为界面稳定剂,通过高速分散结合高压微射流均质技术制备了薄荷醇负载型壳聚糖-肉桂醛界面键合乳液。系统考察了壳聚糖/肉桂醛质量比(1∶0、1∶0.25、1∶0.50、1∶0.75、1∶1.00、1∶1.25)对乳液体系的影响,阐明了乳液的界面特性、粒径分布与zeta电位、微观形貌、流变行为、离心稳定性等乳液结构特性对包封效率及包封稳定性的影响及优化机制。结果表明,肉桂醛的引入显著降低了油-水界面张力,促进了界面吸附。当壳聚糖/肉桂醛质量比为1∶0.75时,乳液的综合性能最优,具体表现为粒径最小(0.36 μm)、包封率最高(78.4%),离心及贮藏稳定性俱佳。激光共聚焦扫描显微镜图像显示此时乳滴分布均匀,无团聚。研究表明,通过界面共价键合反应,适量的肉桂醛可与壳聚糖在界面形成致密稳定的复合膜,而肉桂醛过量则可能会导致壳聚糖分子交联过度,进而导致乳液稳定性降低。该研究为开发高性能薄荷醇输送体系提供了有效的策略和理论依据。
This study aimed to optimize the stability and loading performance of menthol emulsions.Menthol-loaded chitosan-cinnamaldehyde interfacial bond emulsions were prepared using high-speed dispersion followed by high-pressure microfluidization, with chitosan and cinnamaldehyde serving as interfacial stabilizers.The effects of different chitosan-to-cinnamaldehyde mass ratios (1∶0, 1∶0.25, 1∶0.50, 1∶0.75, 1∶1.00, and 1∶1.25) on the emulsion system were systematically investigated.Key structural characteristics, including interfacial properties, droplet size distribution, zeta potential, microstructure, rheological behavior, and centrifugal stability, were analyzed to explore their influence on encapsulation efficiency and storage stability.The results indicated that the incorporation of cinnamaldehyde significantly reduced the oil-water interfacial tension, enhancing interfacial adsorption.When the mass ratio of chitosan to cinnamaldehyde is 1∶0.75, the emulsion exhibited optimal overall performance, characterized by the smallest droplet size (0.36 μm) and the highest encapsulation efficiency (78.4%), along with excellent centrifugal and storage stability.Confocal laser scanning microscopy images revealed uniform droplet distribution with no aggregation.Studies suggested that an appropriate amount of cinnamaldehyde could form a dense, stable composite interfacial film through covalent bonding with chitosan, while excessive cinnamaldehyde caused over-crosslinking of the chitosan molecules, thereby compromising the emulsion’s stability.This work provides an effective strategy and theoretical foundation for the development of high-performance menthol delivery systems.
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