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食品与发酵工业  2019, Vol. 45 Issue (2): 240-246    DOI: 10.13995/j.cnki.11-1802/ts.018169
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玉米赤霉烯酮新型生物传感器检测技术研究进展
谭红霞, 马良*, 郭婷, 陈露, 刘微, 谢盛莉
(西南大学 食品科学学院,重庆,400715)
Research progress of biosensor technology for detecting zearalenone
TAN Hongxia, MA Liang*, GUO Ting, CHEN Lu, LIU Wei, XIE Shengli
(Southwest University School of Food Science, Chongqing 400715, China)
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摘要 玉米赤霉烯酮是由镰刀菌产生的一种类雌激素样真菌毒素,具有流产和雌激素作用、致畸、致癌性以及神经毒性等,其污染严重影响动物源和植物源性食品及原料的安全。高灵敏、强特异性的基于生物传感器的玉米赤霉烯酮检测方法是近年来新兴的有效检测手段。结合近4年来国内外相关研究进展,对检测玉米赤霉烯酮类真菌毒素的电化学生物传感器、荧光生物传感器、核酸适配体生物传感器、细胞传感器等各种生物传感器检测技术进行综述,分析其检测的灵敏度、特异性等特性,并对存在的问题和发展方向进行了讨论与展望。
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谭红霞
马良
郭婷
陈露
刘微
谢盛莉
关键词:  玉米赤霉烯酮  电化学生物传感器  荧光生物传感器  核酸适配体生物传感器  细胞传感器    
Abstract: Zearalenone, an estrogen-like mycotoxin produced by strains from Fusarium sp., causes abortion and has estrogenic, teratogenic, carcinogenic and neurotoxic effects. Its contamination affects the safety of animal and plant-derived foods and raw materials seriously. In recent years, the higher sensitive and specific biosensor used for zearalenone detection is developed and applied. Combining related national and international research achievements in the past four years, biosensor detection technologies such as electrochemical biosensors, fluorescent biosensors, aptamer biosensors and cell sensors. used for detecting zearalenone mycotoxins were reviewed. Their sensitivity, specificity and other characteristics during the detection process were emphasized. Meanwhile, the probable problems and directions for future development were discussed.
Key words:  zearalenone    electrochemical biosensors    fluorescence biosensors    aptamer biosensors    cell sensor
收稿日期:  2018-07-02                出版日期:  2019-01-25      发布日期:  2019-02-21      期的出版日期:  2019-01-25
基金资助: 中央高校基本科研业务费专项(XDJK2017B042);重庆市技术创新与应用示范(社会民生类一般)项目(cstc2018js cx-msyb0804)
作者简介:  教授(马良教授为通讯作者,E-mail:zhyhml@163.com)。
引用本文:    
谭红霞,马良,郭婷,等. 玉米赤霉烯酮新型生物传感器检测技术研究进展[J]. 食品与发酵工业, 2019, 45(2): 240-246.
TAN Hongxia,MA Liang,GUO Ting,et al. Research progress of biosensor technology for detecting zearalenone[J]. Food and Fermentation Industries, 2019, 45(2): 240-246.
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http://sf1970.cnif.cn/CN/10.13995/j.cnki.11-1802/ts.018169  或          http://sf1970.cnif.cn/CN/Y2019/V45/I2/240
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