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食品与发酵工业  2019, Vol. 45 Issue (4): 206-210    DOI: 10.13995/j.cnki.11-1802/ts.017736
  分析与检测 本期目录 | 过刊浏览 | 高级检索 |
采用高灵敏共振光散射技术检测食品中残留的卡马西平
江虹*, 庞向东, 吴小燕, 程丹, 李娜
(长江师范学院 化学化工学院,长江师范学院武陵山片区绿色发展协同创新中心,重庆,408100)
Studies on detecting carbamazepine residues in food using high sensitive resonant light scattering technique
JIANG Hong*, PANG Xiangdong, WU Xiaoyan, CHENG Dan, LI Na
(College of Chemistry and Chemical Engineering, Collaborative Innovation Center for Green Development in Wuling Mountain Areas, Yangtze Normal University, Chongqing 408100,China)
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摘要 在pH 3.46 的酸性介质中,卡马西平与考马斯亮蓝-溴代十六烷基吡啶反应生成离子缔合物,使共振光散射(resonance light scattering, RLS)信号明显增强,在最大共振光散射波长344 nm处,卡马西平的质量浓度在0.006~0.33 mg/L与体系共振光散射强度的增加值(ΔIRLS)呈良好的线性关系,检出限为0.005 6 mg/L,定量限为0.012 mg/kg。据此建立了快速、准确、高灵敏测定肉食中残留卡马西平的RLS新方法。该法用于肉食中残留卡马西平含量的测定,回收率为98.5%~102%,相对标准偏差(n=5)为2.2%~2.6%。
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江虹
庞向东
吴小燕
程丹
李娜
关键词:  卡马西平  考马斯亮蓝  肉食品  药残  高灵敏  共振光散射    
Abstract: In an acidic medium of pH 3.46, carbamazepine reacted with coomassie brilliant blue- cetylpyridyl bromide to form an ion association, which led to the resonance light scattering (RLS) signal increased obviously. At the maximal resonant light scattering wavelength of 344 nm, the mass concentration of carbamazepine in the range of 0.006-0.33 mg/L showed a good linear relationship with the increase in resonant light scattering intensity (ΔIRLS). The detection limit was 0.0056 mg/ L and the limit of quantitation was 0.012 mg/kg. Based on the above results, a rapid, accurate, highly sensitive new RLS method for determining carbamazepine in meat foods was established. This method was applied to determine residual carbamazepine in meat foods with 98.5%-102% recovery rate and the relative standard deviation (n=5) was 2.2%-2.6%.
Key words:  carbamazepine    coomassie brilliant blue    meat food    drug residue    high sensitive    resonance light scattering
收稿日期:  2018-06-08                出版日期:  2019-02-25      发布日期:  2019-03-26      期的出版日期:  2019-02-25
基金资助: 重庆市教委科技基金资助项目(KJ1401226);长江师范学院科技基金资助项目(2017CXX158)
作者简介:  学士,教授(本文通讯作者,E-mail:jianghongch@163.com)。
引用本文:    
江虹,庞向东,吴小燕,等. 采用高灵敏共振光散射技术检测食品中残留的卡马西平[J]. 食品与发酵工业, 2019, 45(4): 206-210.
JIANG Hong,PANG Xiangdong,WU Xiaoyan,et al. Studies on detecting carbamazepine residues in food using high sensitive resonant light scattering technique[J]. Food and Fermentation Industries, 2019, 45(4): 206-210.
链接本文:  
http://sf1970.cnif.cn/CN/10.13995/j.cnki.11-1802/ts.017736  或          http://sf1970.cnif.cn/CN/Y2019/V45/I4/206
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