利用静电纺丝技术制备负载百里香酚的玉米醇溶蛋白基纳米纤维抗菌膜,并研究其微观结构、表面接触角、水汽透过率和抗菌物质释放率等性质。实验结果表明,当玉米醇溶蛋白与百里香酚质量比为10∶1时,纳米纤维膜具有一定缓释抗菌物质的能力,其水汽透过率为4.32 g·mm/(m2·h·kPa),表面接触角为104.36°,表明该膜具有良好的透气性及疏水稳定性,且由于其安全性特别适合医用敷料等方面的应用。当玉米醇溶蛋白与百里香酚质量比为5∶1~1∶1时,纳米纤维抗菌膜对大肠杆菌有一定的抗菌效果,最小抑菌圈直径为8.68 mm,最大抑菌圈直径为20.42 mm。
Zein-thymol nanofiber films were prepared by electrospinning in this study. The microstructure, contact angle, water vapor transmission rate, and the rate of releasing anti-bacterial substances from the film were investigated. The results showed that when the mass ratio of zein to thymol was 10∶1, the film exhibited a slow-releasing property. Moreover, the water vapor transmission rate of the film was 4.32 g·mm/(m2·h·kPa), and the contact angle was 104.36°. This demonstrated that the zein-thymol nanofiber film had good air permeability and hydrophobicity. Furthermore, the antibacterial effect of the film on Escherichia coli was effective when the ratio of zein to thymol was in a range of 5∶1-1∶1. The minimum and maximum diameters of inhibition zone was 8.68 mm and 20.42 mm, respectively. Besides, due to the safety of the film, it is suitable for medical purpose, such as medical wound dressings.
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