[1] WANG Z, CHEN Z, ZHANG L, et al.Status of hypertension in China: Results from the China hypertension survey, 2012-2015[J]. Circulation, 2018, 137(22): 2 344-2 356.
[2] BHAT Z F, KUMAR S, BHAT H F.Antihypertensive peptides of animal origin: A review[J]. Critical Reviews in Food Science and Nutrition, 2017, 57(3): 566-578.
[3] GU Y C, WU J P.LC-MS/MS coupled with QSAR modeling in characterising of angiotensin I-converting enzyme inhibitory peptides from soybean proteins[J]. Food Chemistry, 2013, 141(3): 2 682-2 690.
[4] COOPER W O, HERNANDEZ-DIAZ S, ARBOGAST P G, et al.Major congenital malformations after first-trimester exposure to ACE inhibitors[J]. The New England Journal of Medicine, 2006, 354(23): 2 443-2 451.
[5] 田明慧, 林亲录, 梁盈, 等. 植物源性食物中活性肽氨基酸组成的研究进展[J]. 食品与发酵工业,2014, 40(6): 110-116.
[6] TOUYZ R M, BRIONES A M.Reactive oxygen species and vascular biology: implications in human hypertension[J]. Hypertension Research, 2011, 34(1): 5-14.
[7] POPOLO A, AUTORE G, PINTO A, et al.Oxidative stress in patients with cardiovascular disease and chronic renal failure[J]. Free Radical Research, 2013, 47(5): 346-356.
[8] CHEN K, XIE F, LIU S, et al.Plasma reactive carbonyl species: Potential risk factor for hypertension[J]. Free Radical Research, 2011, 45(5): 568-574.
[9] GARCIA-MORA P, PEÑAS E, FRIAS J, et al. High-pressure improves enzymatic proteolysis and the release of peptides with angiotensin I converting enzyme inhibitory and antioxidant activities from lentil proteins[J]. Food Chemistry, 2015, 171: 224-232.
[10] TANZADEHPANAH H, ASOODEH A, SAIDIJAM M, et al.Improving efficiency of an angiotensin converting enzyme inhibitory peptide as multifunctional peptides[J]. Journal of Biomolecular Structure and Dynamics, 2017, 36(14): 3 803-3 818.
[11] LU X, ZHANG L X, SUN Q, et al.Extraction, identification and structure-activity relationship of antioxidant peptides from sesame (Sesamum indicum L.) protein hydrolysate[J]. Food Research International, 2019, 116: 707-716.
[12] NAKANO D, OGURA K, MIYAKOSHI M, et al.Antihypertensive effect of angiotensin I-converting enzyme inhibitory peptides from a sesame protein hydrolysate in spontaneously hypertensive rats[J]. Bioscience Biotechnology and Biochemistry, 2006, 70(5): 1 118-1 126.
[13] 袁东振, 张国治, 黄纪念, 等. 用亚临界芝麻粕制备芝麻蛋白的工艺研究[J]. 河南工业大学学报(自然科学版), 2014, 35(6): 49-55.
[14] 周存山, 秦晓佩, 余筱洁, 等. 绿鳍马面鲀鱼皮蛋白抗氧化肽模拟胃肠消化制备[J]. 农业机械学报, 2015, 46(8): 211-216.
[15] VUKIC V R, VUKIC D V, MILANOVIC S D, et al.In silico identification of milk antihypertensive di-and tripeptides involved in angiotensin I-converting enzyme inhibitory activity[J]. Nutrition Research, 2017, 46: 22-30.
[16] SEKO T, IMAMURA S, ISHIHARA K.et al.Inhibition of angiotensin-converting enzyme by selenoneine[J]. Fisheries Science, 2019, 85: 731-736.
[17] 杨欣, 李亚辉, 钱海兵, 等. 基于网络药理学筛选结肠癌关键靶点及人参干预研究[J]. 贵阳中医学院学报, 2019, 41(6):24-30.
[18] LAFARGA T, WILM M, WYNNE K, et al.Bioactive hydrolysates from bovine blood globulins: Generation, characterisation, and in silico prediction of toxicity and allergenicity[J]. Journal of Functional Foods, 2016, 24: 142-155.
[19] 李致瑜, 张翀, 田玉庭, 等. 大黄鱼内脏抗氧化肽的稳定性研究[J]. 现代食品科技, 2016, 32(1): 151-158.
[20] LI F J, YIN L J, LU X, et al.Changes in angiotensin I-converting enzyme inhibitory activities during the ripening of Douchi (a Chinese traditional soybean product) fermented by various starter cultures[J]. International Journal of Food Properties, 2010, 13(3): 512-524.
[21] UDENIGWE C C, ALUKO R E.Chemometric analysis of the amino acid requirements of antioxidant food protein hydrolysates[J]. International Journal of Molecular Sciences, 2011, 12: 3 148-3 161.
[22] TIAN M, FANG B, JIANG L, et al.Structure-activity relationship of a series of antioxidant tripeptides derived from β-lactoglobulin using QSAR modeling[J]. Dairy Science and Technology, 2015, 95: 451-463
[23] GÓMEZ-RUIZ J A, TABORDA G, AMIGO L, et al. Identification of ACE-inhibitory peptides in different Spanish cheeses by tandem mass spectrometry[J]. European Food Research and Technology, 2006, 223: 595-601.
[24] TERASHIMA M, BABA T, IKEMOTO N, et al.Novel angiotensin-converting enzyme (ACE) inhibitory peptides derived from boneless chicken leg meat[J]. Journal of Agricultural and Food Chemistry, 2010, 58: 7 432-7 436.
[25] SAITO T, NAKAMURA T, KITAZAWA H, et al.Isolation and structural analysis of antihypertensive peptides that exist naturally in Gouda cheese[J]. Journal of Dairy Science, 2000, 83: 1 434-1 440.
[26] VILLEGAS J M, PICARIELLO G, MAMONE G, et al.Milk-derived angiotensin-I-converting enzyme-inhibitory peptides generated by Lactobacillus delbrueckii subsp. lactis CRL 581[J]. Peptidomics, 2014, 1: 22-29.
[27] 管骁, 刘静, 苏淅娜, 等. 血管紧张素转化酶抑制二肽抑制ACE作用的柔性分子拼接[J]. 食品科学, 2015, 36(5): 1-6.
[28] 张晖, 唐文婷, 王立, 等. 抗氧化肽的构效关系研究进展[J]. 食品与生物技术学报, 2013, 32(7): 673-679.
[29] ALUKO R E.Structure and function of plant protein-derived antihypertensive peptides[J]. Current Opinion in Food Science, 2015, 4: 44-50.
[30] LIU C L, FANG L, MIN W H, et al.Exploration of the molecular interactions between angiotensin-I-converting enzyme (ACE) and the inhibitory peptides derived from hazelnut (Corylus heterophylla Fisch.)[J]. Food Chemistry, 2018, 245: 471-480.
[31] WU J P, ALUKO R, NAKAI S.Structural requirements of angiotensin I-converting enzyme inhibitory peptides: Quantitative structure activity relationship modeling of peptides containing 4-10 amino acid residues[J]. QSAR & Combinatorial Science, 2006, 25(10): 873-880.
[32] UDENIGWE C C, LI H, ALUKO R E.Quantitative structure-activity relationship modeling of renin-inhibiting dipeptides[J]. Amino Acids, 2012, 42(4): 1 379-1 386.
[33] PINA A S, ROQUE A C A. Studies on the molecular recognition between bioactive peptides and angiotensin-converting enzyme[J]. Journal of Molecular Recognition, 2009, 22(2): 162-168.
[34] 朱义福. 还原型谷胱甘肽的稳定性研究[J]. 现代食品科技, 2011, 27(8): 919-923.
[35] 胡晓, 吴静, 杨贤庆, 等. 添加物和体外模拟胃肠道消化对鸢乌贼抗氧化肽稳定性的影响[J]. 食品与发酵工业, 2016, 42(11): 91-96.
[36] 王辉, 冯万祥. 含汞树脂分离提纯谷胱甘肽[J]. 华东理工大学学报, 1996, 22(6): 717-721.
[37] CHONDROGIANNI N, PETROPOULOS I, GRIMM S, et al.Protein damage, repair and proteolysis[J]. Molecular Aspects of Medicine, 2014, 35:1-71.