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金属纳米颗粒-刺激响应型水凝胶:活性成分递送体系研究进展

  • 刘梦聪 ,
  • 蒋玲 ,
  • 饶哲楠 ,
  • 王启明 ,
  • 陈媛媛 ,
  • 雷小娟 ,
  • 明建
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  • 1(西南大学 食品科学学院,重庆,400715)
    2(川渝共建特色食品重庆市重点实验室,重庆,400715)
第一作者:硕士研究生(明建教授为通信作者,E-mail:mingjian1972@163.com)

收稿日期: 2022-07-13

  修回日期: 2022-08-10

  网络出版日期: 2023-09-27

基金资助

国家自然科学基金面上项目(31771970)

Metal nanoparticle-stimulus-responsive hydrogel composites: Research of active components delivery system

  • LIU Mengcong ,
  • JIANG Ling ,
  • RAO Zhenan ,
  • WANG Qiming ,
  • CHEN Yuanyuan ,
  • LEI Xiaojuan ,
  • MING Jian
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  • 1(College of Food Science, Southwest University, Chongqing 400715, China)
    2(Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Chongqing 400715, China)

Received date: 2022-07-13

  Revised date: 2022-08-10

  Online published: 2023-09-27

摘要

刺激响应型水凝胶活性成分递送体系因其对不同环境具有独特的溶胀和降解特性,在食品、医药等领域已有广泛研究。然而,部分水凝胶作为活性成分递送载体时存在荷载效率和靶向释放效率低等问题。基于金属纳米颗粒具有高比表面积和多孔结构的特点,可增强刺激响应型水凝胶的活性成分荷载能力。将金属纳米颗粒和刺激响应型水凝胶杂化制备得到的复合材料,在环境响应型的活性成分递送和控制释放领域已得到大量研究。论文综述了金属纳米颗粒-刺激响应型水凝胶复合材料的特点、种类和制备方法,总结了其在活性成分递送领域的应用,并对其作为递送体系的未来发展进行了展望。

本文引用格式

刘梦聪 , 蒋玲 , 饶哲楠 , 王启明 , 陈媛媛 , 雷小娟 , 明建 . 金属纳米颗粒-刺激响应型水凝胶:活性成分递送体系研究进展[J]. 食品与发酵工业, 2023 , 49(17) : 340 -347 . DOI: 10.13995/j.cnki.11-1802/ts.032972

Abstract

The stimulus-responsive hydrogel active components delivery system has been widely used in food, medicine, and other fields because of its unique swelling and degradation characteristics in different environments. However, some hydrogels have some problems such as low active components loading rate and low targeting release efficiency when they are used as active components delivery carriers. Based on the characteristics of high surface area and porous structure, metal nanoparticles can enhance the active component loading capacity of stimulus-responsive hydrogels. The composites prepared by the hybrid of metal nanoparticles and stimulus-responsive hydrogels have been widely studied in the field of environmentally responsive active components delivery and controlled release. This paper mainly reviewed the characteristics, types, and preparation methods of metal nanoparticles-stimulus-responsive hydrogel composites, summarized their applications in the field of active components delivery, and prospected their future development as the delivery system.

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