综述与专题评论

桑资源生物活性物质及其在食品领域应用研究进展

  • 黄越 ,
  • 黄传书 ,
  • 吴均 ,
  • 戴宏杰
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  • 1(重庆市蚕业科学技术研究院,重庆,400700)
    2(西南大学 食品科学学院,重庆,400715)
第一作者:硕士,工程师(戴宏杰副教授为通信作者,E-mail:daihjdemo@163.com)

收稿日期: 2022-12-01

  修回日期: 2023-01-12

  网络出版日期: 2024-01-02

基金资助

重庆市科研机构绩效激励引导专项(cstc2022jxjl00015);国家自然科学基金项目(31901683);中央高校基本科研业务费专项资金资助(SWU-KT22046)

Research progress on bioactive substances of mulberry resources and their application in food field

  • HUANG Yue ,
  • HUANG Chuanshu ,
  • WU Jun ,
  • DAI Hongjie
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  • 1(Chongqing Sericulture Science and Technology Research Institute, Chongqing 400700, China)
    2(College of Food Science, Southwest University, Chongqing 400715, China)

Received date: 2022-12-01

  Revised date: 2023-01-12

  Online published: 2024-01-02

摘要

桑资源主要包括桑椹、桑叶、桑黄、桑白皮等,集合桑资源的高值化综合利用对桑产业的可持续发展具有重要意义。该文介绍了近年来研究较多的桑资源及其含有的生物活性物质如多糖、多酚、生物碱、萜类、蛋白质和多肽等,并对桑资源生物活性物质在食品领域的应用进行了介绍。本综述旨在为桑资源的深加工利用及相关功能性食品的研发提供借鉴与参考,助推桑产业可持续发展。

本文引用格式

黄越 , 黄传书 , 吴均 , 戴宏杰 . 桑资源生物活性物质及其在食品领域应用研究进展[J]. 食品与发酵工业, 2023 , 49(23) : 362 -370 . DOI: 10.13995/j.cnki.11-1802/ts.034496

Abstract

Mulberry resources mainly contain mulberry fruits, mulberry leaves, Phellinus igniarius, Mori Cortex, etc. The high-value comprehensive utilization of mulberry resources is of great significance to the sustainable development of the mulberry industry. This review introduced the mulberry resources that have been studied extensively in recent years and their bioactive substances such as polysaccharides, polyphenols, alkaloids, terpenoids, proteins, and polypeptides. The applications of bioactive substances of mulberry resources in the food field were also summarized. This review aimed to provide a reference for the deep processing utilization as well as the research and development of related functional food of mulberry resources, thus promoting the development of the mulberry industry.

参考文献

[1] 李来成, 张士凯, 许方舟, 等.桑叶综合利用的研究进展[J].食品工业科技, 2022, 43(2):397-404.
LI L C, ZHANG S K, XU F Z, et al.Research progress of mulberry leaf comprehensive utilization[J].Science and Technology of Food Industry, 2022, 43(2):397-404.
[2] 钟熙, 杨鹤, 柯晓雪, 等.桑树化学成分及药理活性研究进展[J].中国中药杂志, 2022, 47(9):2373-2391.
ZHONG X, YANG H, KE X X, et al.Research progress on chemical constituents and pharmacological activities of Morus alba[J].China Journal of Chinese Materia Medica, 2022, 47(9):2373-2391.
[3] KHALIFA I, ZHU W, LI K K, et al.Polyphenols of mulberry fruits as multifaceted compounds:Compositions, metabolism, health benefits, and stability:A structural review[J].Journal of Functional Foods, 2018, 40:28-43.
[4] AJAY KRISHNA P G, SIVAKUMAR T R, JIN C,et al.Antioxidant and hemolysis protective effects of polyphenol-rich extract from mulberry fruits[J].Pharmacognosy Magazine, 2018, 14(53):103-109.
[5] 曾卫湘. 53份桑资源叶的药用品质评价[D].重庆:西南大学, 2017.
ZENG W X.Evaluation of medicinal quality of 53 mulberry leaves[D].Chongqing:Southwest University, 2017.
[6] YING Z, HAN X X, LI J R.Ultrasound-assisted extraction of polysaccharides from mulberry leaves[J].Food Chemistry, 2011, 127(3):1273-1279.
[7] CAO Y, JIANG W, BAI H X, et al.Study on active components of mulberry leaf for the prevention and treatment of cardiovascular complications of diabetes[J].Journal of Functional Foods, 2021, 83:104549.
[8] LI Y G, JI D F, ZHONG S, et al.1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice[J].Scientific Reports, 2013, 3:1377.
[9] 齐欣, 张峻, 陈颖, 等.六种不同树种桑黄有效成分的比较[J].食品科学, 2010, 31(6):199-201.
QI X, ZHANG J, CHEN Y, et al.Comparative analysis of bioactive components in fruit bodies of Phellinus linteus growing on six species of trees[J].Food Science, 2010, 31(6):199-201.
[10] 钟石, 李有贵, 林天宝, 等.桑黄多糖P1对肝癌HepG2细胞周期和钙调蛋白信号通路的影响[J].中国药理学与毒理学杂志, 2015, 29(3):417-423.
ZHONG S, LI Y G, LIN T B, et al.Effect of polysaccharide P1 from Phellinus linteus on cell cycle and calcium/calmodulin-dependent protein signal pathway in HepG2 cells[J].Chinese Journal of Pharmacology and Toxicology, 2015, 29(3):417-423.
[11] 王聪聪, 马永昆, 许满青, 等.桑椹浆果及其生物发酵制品研究进展[J].食品研究与开发, 2023, 44(10):215-219.
WANG C C, MA Y K, XU M Q, et al.Research progress of mulberry berry and biological fermentation products[J].Food Research and Development, 2023, 44(10):215-219.
[12] 佟万红, 曾益春, 黄盖群.四川省果桑产业的现状与发展建议[J].蚕学通讯, 2021, 41(2):15-19.
TONG W H, ZENG Y C, HUANG G Q.The Current situation and suggestions of the fruit mulberry industry development in Sichuan Province[J].Newsletter of Sericultural Science, 2021, 41(2):15-19.
[13] YUAN Q X, ZHAO L Y.The mulberry (Morus alba L.) fruit:A review of characteristic components and health benefits[J].Journal of Agricultural and Food Chemistry, 2017, 65(48):10383-10394.
[14] JAN B, PARVEEN R, ZAHIRUDDIN S, et al.Nutritional constituents of mulberry and their potential applications in food and pharmaceuticals:A review[J].Saudi Journal of Biological Sciences, 2021, 28(7):3909-3921.
[15] 樊志彤. 桑树不同品种果实品质分析及综合评价[D].保定:河北农业大学, 2019.
FAN Z T.Analysis and comprehensive evaluation of fruit quality of different mulberry varieties[D].Baoding:Hebei Agricultural University, 2019.
[16] 殷浩, 佟万红, 王振江, 等.桑椹成熟过程中部分活性成分的含量变化[J].蚕业科学, 2011, 37(6):1106-1110.
YIN H, TONG W H, WANG Z J, et al.Content variation of active components in mulberry fruit during maturation[J].Science of Sericulture, 2011, 37(6):1106-1110.
[17] 何雪梅, 孙健, 梁贵秋, 等.广西地区13个主栽桑品种的桑椹营养与药用品质综合评价[J].食品科学, 2018, 39(10):250-256.
HE X M, SUN J, LIANG G Q, et al.Nutritional and medicinal quality of mulberry fruit from 13 main varieties grown in Guangxi[J].Food Science, 2018, 39(10):250-256.
[18] 杜晓童, 刘凡, 沈维治, 等.新疆药桑椹主要营养活性成分分析及体外抗炎作用[J].蚕业科学, 2020, 46(3):306-312.
DU X T, LIU F, SHEN W Z, et al.Main nutritional components in fruit of Xinjiang black mulberry(Morus nigra L.)and their in vitro anti-inflammatory activity[J].Science of Sericulture, 2020, 46(3):306-312.
[19] 温靖, 徐玉娟, 肖更生, 等.6个果桑品种的桑果加工品质性状测定与分析[J].蚕业科学, 2015, 41(1):107-111.
WEN J, XU Y J, XIAO G S, et al.Determination and analysis of processing characteristics of six mulberry varieties for fruit use[J].Science of Sericulture, 2015, 41(1):107-111.
[20] 俞燕芳, 黄金枝, 石旭平, 等.我国桑叶食品开发研究进展[J].食品安全质量检测学报, 2018, 9(7):1572-1578.
YU Y F, HUANG J Z, SHI X P, et al.Research progress in food development of mulberry leaves in China[J].Journal of Food Safety & Quality, 2018, 9(7):1572-1578.
[21] 马飞跃, 耿炬, 乔健, 等.不同品种桑葚叶总酚含量及其抗氧化活性比较[J].热带作物学报, 2021, 42(3):888-896.
MA F Y, GENG J, QIAO J, et al.Comparison of total phenol content and antioxidant activity from different mulberry leaves[J].Chinese Journal of Tropical Crops, 2021, 42(3):888-896.
[22] 汤晶晶, 缪婧, 崔月花.不同培养模式下桑黄挥发性风味物质的检测和分析[J].食品与发酵工业, 2019, 45(14):221-228.
TANG J J, MIAO J, CUI Y H.Analysis of volatile flavor compounds in Phellinus linteus at various cultivation modes[J].Food and Fermentation Industries, 2019, 45(14):221-228.
[23] 杨焱, 陈晓华, 戴玉成, 等.我国桑黄产业发展现状、问题及展望:桑黄产业发展千岛湖宣言[J].菌物学报, 2023, 42(4):855-873.
YANG Y, CHEN X H, DAI Y C, et al.Sanghuang industry in China:Current status, challenges and perspectives:The Qiandao Lake declaration for Sanghuang industry development[J].Mycosystema, 2023, 42(4):855-873.
[24] YANG N C, WU C C, LIU R H, et al.Comparing the functional components, SOD-like activities, antimutagenicity, and nutrient compositions of Phellinus igniarius and Phellinus linteus mushrooms[J].Journal of Food and Drug Analysis, 2016, 24(2):343-349.
[25] 刘滢, 董金香, 高原, 等.基于多指标综合评价炒桑白皮炮制工艺研究[J].时珍国医国药, 2022, 33(9):2150-2153.
LIU Y, DONG J X, GAO Y, et al.Study on processing technology of fried mulberry bark based on multi-index comprehensive evaluation[J].Lishizhen Medicine and Materia Medica Research, 2022, 33(9):2150-2153.
[26] 丁倩云, 马双成, 许风国, 等.桑白皮的化学成分、药理及质量控制研究进展[J].药物分析杂志, 2021, 41(7):1114-1124.
DING Q Y, MA S C, XU F G, et al.Research progress on chemical constituents, pharmacology, and quality control of Mori Cortex[J].Chinese Journal of Pharmaceutical Analysis, 2021, 41(7):1114-1124.
[27] 郑甜碧, 万晶琼, 杨翠云, 等.基于HPLC-ESI-MS技术的桑白皮、桑根皮及外粗皮主要成分定性与定量研究[J].中国中药杂志, 2021, 46(9):2237-2244.
ZHENG T B, WAN J Q, YANG C Y, et al.Systematic analysis on chemical constituents of Mori Cortex, mulberry root bark and its phellem layer based on HPLC-ESI-MS[J].China Journal of Chinese Materia Medica, 2021, 46(9):2237-2244.
[28] 杨斯惠, 向月, 曹亚楠, 等.植物多糖的益生作用及其影响因素研究进展[J].食品科学, 2022, 43(11):301-310.
YANG S H, XIANG Y, CAO Y N, et al.Progress in research on the prebiotic effects of plant polysaccharides and the factors influencing them[J].Food Science, 2022, 43(11):301-310.
[29] 王文丽, 张金玲, 魏亚宁, 等.天然多糖提取、纯化及生物活性研究进展[J].食品工业科技, 2022, 43(22):470-480.
WANG W L, ZHANG J L, WEI Y N, et al.Research progress on extraction, purification and biological activity of natural polysaccharides:A review[J].Science and Technology of Food Industry, 2022, 43(22):470-480.
[30] 杨斌旺, 刘平古, 刘龙飞, 等.药桑叶多糖的脱蛋白工艺与抗氧化活性研究[J].食品研究与开发, 2020, 41(10):156-160.
YANG B W, LIU P G, LIU L F, et al.Study on deproteinization process and antioxidant activity of polysaccharide from Morus nigra leaves[J].Food Research and Development, 2020, 41(10):156-160.
[31] ZHANG Y, REN C J, LU G B, et al.Purification, characterization and anti-diabetic activity of a polysaccharide from mulberry leaf[J].Regulatory Toxicology and Pharmacology, 2014, 70(3):687-695.
[32] 孙伟, 叶润, 蔡静, 等.桑叶多糖的分离纯化及其抑菌活性研究[J].食品研究与开发, 2021, 42(4):149-155.
SUN W, YE R, CAI J, et al.Purification and antibacterial activity of polysaccharide from mulberry leaves[J].Food Research and Development, 2021, 42(4):149-155.
[33] 陈永丽, 黄俊僮, 王玲, 等.桑叶多糖的化学组成及其对胰脂肪酶的抑制作用研究[J].食品科技, 2021, 46(3):162-166.
CHEN Y L, HUANG J T, WANG L, et al.Chemical composition of mulberry leaf polysaccharide and its inhibitory effect on pancreatic lipase[J].Food Science and Technology, 2021, 46(3):162-166.
[34] CHEN C, YOU L J, ABBASI A M, et al.Characterization of polysaccharide fractions in mulberry fruit and assessment of their antioxidant and hypoglycemic activities in vitro[J].Food & Function, 2016, 7(1):530-539.
[35] WANG Y, XIE Y, WANG A D, et al.Insights into interactions between food polyphenols and proteins:An updated overview[J].Journal of Food Processing and Preservation, 2022, 46(5):e16597.
[36] LI R, ZHU Q B, WANG X Y, et al.Mulberry leaf polyphenols alleviated high-fat diet-induced obesity in mice[J].Frontiers in Nutrition, 2022, 9:979058.
[37] LI C, PENG Y, TANG W, et al.Antioxidant, anti-lipidemic, hypoglycemic and antiproliferative effects of phenolics from cortex Mori radicis[J].Arabian Journal of Chemistry, 2022, 15(6):103824.
[38] 刘慧, 穆同娜, 林立, 等.新兴食品安全潜在风险因子生物碱成分的研究进展[J].食品工业科技, 2023, 44(8):485-494.
LIU H, MU T N, LIN L, et al.Research progress on alkaloids as emerging potential risk factors for food safety[J].Science and Technology of Food Industry, 2023, 44(8):485-494.
[39] GE Q, CHEN L, TANG M, et al.Analysis of mulberry leaf components in the treatment of diabetes using network pharmacology[J].European Journal of Pharmacology, 2018, 833:50-62.
[40] WANG Y T, YU Z W, JIANG J, et al.Mulberry leaf attenuates atherosclerotic lesions in patients with coronary heart disease possibly via 1-Deoxynojirimycin:A placebo-controlled, double-blind clinical trial[J].Journal of Food Biochemistry, 2021, 45(1):e13573.
[41] LIU C, XIANG W, YU Y, et al.Comparative analysis of 1-deoxynojirimycin contribution degree to α-glucosidase inhibitory activity and physiological distribution in Morus alba L.[J].Industrial Crops and Products, 2015, 70:309-315.
[42] LI Y G, ZHONG S, YU J Q, et al.The mulberry-derived 1-deoxynojirimycin (DNJ) inhibits high-fat diet (HFD)-induced hypercholesteremia and modulates the gut microbiota in a gender-specific manner[J].Journal of Functional Foods, 2019, 52:63-72.
[43] HAN X Y, SONG C Y, FENG X X, et al.Isolation and hypoglycemic effects of water extracts from mulberry leaves in Northeast China[J].Food & Function, 2020, 11(4):3112-3125.
[44] 刘庆普, 陈燕, 谢彩侠, 等.桑叶生物碱对小鼠酒精性肝损伤的保护作用[J].现代食品科技, 2022, 38(6):1-8.
LIU Q P, CHEN Y, XIE C X, et al.Ameliorative effect of mulberry leaf alkaloids on alcoholic liver injury in mice[J].Modern Food Science and Technology, 2022, 38(6):1-8.
[45] 何策, 王超, 陈纯, 等.桑树桑黄总三萜提取工艺优化及其降血脂、抗氧化活性研究[J].食品工业科技, 2021, 42(7):208-215.
HE C, WANG C, CHEN C, et al.Optimization of extraction technology of total triterpenoids from Inonotus sanghuang and their hypolipidemic and antioxidant activities[J].Science and Technology of Food Industry, 2021, 42(7):208-215.
[46] 刘锦良, 沈衡平, 刘辉, 等.大蒜多肽提取工艺的优化及其体外活性的测定[J].食品研究与开发, 2022, 43(19):166-173.
LIU J L, SHEN H P, LIU H, et al.Optimization of extraction technology of garlic polypeptide and determination of its activity in vitro[J].Food Research and Development, 2022, 43(19):166-173.
[47] 余刚, 邱茂慈, 孟彩婷, 等.桑叶酶解产物的制备及其抗氧化活性评价[J].蚕业科学, 2020, 46(4):485-492.
YU G, QIU M C, MENG C T, et al.Preparation of enzymatic hydrolysate of mulberry leaf and evaluation of its antioxidant activity[J].Acta Sericologica Sinica, 2020, 46(4):485-492.
[48] 贾漫丽, 范伟, 李娜, 等.桑叶蛋白血管紧张素转换酶抑制肽的酶解制备[J].蚕业科学, 2021, 47(4):351-357.
JIA M L, FAN W, LI N, et al.Preparation of mulberry leaf protein ACE inhibitory peptide by enzymatic hydrolysis[J].Acta Sericologica Sinica, 2021, 47(4):351-357.
[49] SUN C Z, WU W J, MA Y R, et al.Physicochemical, functional properties, and antioxidant activities of protein fractions obtained from mulberry (Morus atropurpurea Roxb.) leaf[J].International Journal of Food Properties, 2017, 20(3):S3311-S3325.
[50] 蒋光阳, 侯晓艳, 任文, 等.淀粉-羧甲基纤维素钠-花青素指示膜的制备及在鱼肉鲜度指示中的应用[J].食品科学, 2020, 41(12):250-258.
JIANG G Y, HOU X Y, REN W, et al.Preparation of indicator films based on sodium carboxymethyl cellulose/starch and purple sweet potato anthocyanins for monitoring fish freshness[J].Food Science, 2020, 41(12):250-258.
[51] ZHENG T T, TANG P P, LI G Y.Development of a pH-sensitive film based on collagen/chitosan/ZnO nanoparticles and mulberry extract for pork freshness monitoring[J].Food Chemistry, 2023, 402:134428.
[52] ZENG P, CHEN X, QIN Y R, et al.Preparation and characterization of a novel colorimetric indicator film based on gelatin/polyvinyl alcohol incorporating mulberry anthocyanin extracts for monitoring fish freshness[J].Food Research International, 2019, 126:108604.
[53] NEVES D, ANDRADE P B, VIDEIRA R A, et al.Berry anthocyanin-based films in smart food packaging:A mini-review[J].Food Hydrocolloids, 2022, 133:107885.
[54] LIU Y P, QIN Y, BAI R Y, et al.Preparation of pH-sensitive and antioxidant packaging films based on κ-carrageenan and mulberry polyphenolic extract[J].International Journal of Biological Macromolecules, 2019, 134:993-1001.
[55] SHIVANGI S, DORAIRAJ D, NEGI P S, et al.Development and characterisation of a pectin-based edible film that contains mulberry leaf extract and its bio-active components[J].Food Hydrocolloids, 2021, 121:107046.
[56] XU L, ZHU M J, LIU X M, et al.Inhibitory effect of mulberry (Morus alba) polyphenol on the lipid and protein oxidation of dried minced pork slices during heat processing and storage[J].LWT, 2018, 91:222-228.
[57] CHENG J R, XU L, XIANG R, et al.Effects of mulberry polyphenols on oxidation stability of sarcoplasmic and myofibrillar proteins in dried minced pork slices during processing and storage[J].Meat Science, 2020, 160:107973.
[58] 冀冰聪, 杜婷.桑椹花青素的研究现状及其在食品领域中的应用[J].食品研究与开发, 2021, 42(15):189-197.
JI B C, DU T.Research progress on mulberry fruit anthocyanins and their application in the food industry[J].Food Research and Development, 2021, 42(15):189-197.
[59] 陈文庭, 邢朝宏, 周泽琳.食品添加剂桑椹红产品标准的制定[J].食品安全质量检测学报, 2021, 12(13):5139-5144.
CHEN W T, XING C H, ZHOU Z L.Establishment of product standard for food additives mulberry red[J].Journal of Food Safety & Quality, 2021, 12(13):5139-5144.
[60] KANOKPANONT S, YAMDECH R, ARAMWIT P.Stability enhancement of mulberry-extracted anthocyanin using alginate/chitosan microencapsulation for food supplement application[J].Artificial Cells, Nanomedicine, and Biotechnology, 2018, 46(4):773-782.
[61] 唐罗, 陈晓霞, 陈军, 等.桑椹花青素加工稳定性及其应用研究进展[J].食品与发酵工业, 2022:1-13.
TANG L, CHEN X X, CHEN J, et al.Research progress on processing stability and application of mulberry anthocyanins[J].Food and Fermentation Industries, 2022:1-13.
[62] 汤小玉, 魏安琪, 李曙光, 等.三种天然食品添加剂抑制自由基损伤能力的研究[J].化学与生物工程, 2018, 35(7):15-20.
TANG X Y, WEI A Q, LI S G, et al.Inhibition effect of three natural food additives on free radical injury[J].Chemistry & Bioengineering, 2018, 35(7):15-20.
[63] 许健豪. 桑叶γ-氨基丁酸的富集及功能食品的利用研究[D].广州:华南农业大学, 2017.
XU J H.Study on enrichment of γ-aminobutyric acid in mulberry leaves and utilization of functional food[D].Guangzhou:South China Agricultural University, 2017.
[64] SHENG Y, ZHENG S J, ZHANG C H, et al.Mulberry leaf tea alleviates diabetic nephropathy by inhibiting PKC signaling and modulating intestinal flora[J].Journal of Functional Foods, 2018, 46:118-127.
[65] BANG S I, KIM H Y, SEO W T, et al.Mulberry vinegar attenuates lipopolysaccharide and interferon gamma-induced inflammatory responses in C6 glial cells[J].Journal of Food Biochemistry, 2022, 46(8):e14197.
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