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植物蛋白基复合纳米颗粒制备及在生物活性物质递送中的应用

  • 刘燕 ,
  • 刘章会 ,
  • 蒋玲 ,
  • 王启明 ,
  • 饶哲楠 ,
  • 雷小娟 ,
  • 明建
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  • 1(西南大学 食品科学学院,重庆,400715)
    2(川渝共建特色食品重庆市重点实验室,重庆,400715)
第一作者:硕士研究生(明建教授为通信作者,E-mail:mingjian1972@163.com)

收稿日期: 2023-08-15

  修回日期: 2023-09-11

  网络出版日期: 2024-08-02

基金资助

国家自然科学基金面上项目(32272308)

Preparation and application of plant protein-based composite nanoparticles in delivery of bioactive substances: A review

  • LIU Yan ,
  • LIU Zhanghui ,
  • JIANG Ling ,
  • WANG Qiming ,
  • RAO Zhenan ,
  • LEI Xiaojuan ,
  • MING Jian
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  • 1(College of Food Science, Southwest University, Chongqing 400715, China)
    2(Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Chongqing 400715, China)

Received date: 2023-08-15

  Revised date: 2023-09-11

  Online published: 2024-08-02

摘要

多酚、精油、维生素等生物活性物质具有抗氧化、抗炎、预防慢性疾病等功效,但是它们存在溶解度低、稳定性差、生物利用度低等缺陷。研究发现植物蛋白基纳米颗粒是递送生物活性物质的良好材料。然而,使用单一的植物蛋白基纳米颗粒存在包埋率低、不稳定、易受外界环境影响等问题。植物蛋白和其他生物聚合物(包括蛋白质、多糖、多酚、表面活性剂等)结合,整合了多种生物聚合物的优点,可以克服单一蛋白质的不足,具有良好的发展前景。该文综述了植物蛋白基复合纳米颗粒的分类、制备方法及其在生物活性物质递送方面的应用现状,并对植物蛋白基复合纳米颗粒的发展前景进行了展望。

本文引用格式

刘燕 , 刘章会 , 蒋玲 , 王启明 , 饶哲楠 , 雷小娟 , 明建 . 植物蛋白基复合纳米颗粒制备及在生物活性物质递送中的应用[J]. 食品与发酵工业, 2024 , 50(14) : 349 -356 . DOI: 10.13995/j.cnki.11-1802/ts.037063

Abstract

Bioactive substances such as polyphenols, essential oils, and vitamins, have antioxidant, anti-inflammatory, and preventive effects on chronic diseases, but they have defects such as low solubility, poor stability, and low bioavailability.Plant protein-based nanoparticles have been found to be good materials for delivering bioactive substances.However, the use of single plant protein-based nanoparticles has problems such as low embedding rate, instability, and susceptibility to the external environment.The combination of plant protein and other biopolymers (including proteins, polysaccharides, polyphenols, surfactants, etc.) integrates the advantages of a variety of biopolymers, which can overcome the shortcomings of a single protein and has good development prospects.In this article, the classification and preparation methods of plant protein-based composite nanoparticles and their application status in the delivery of bioactive substances were reviewed and the development prospects of plant protein-based composite nanoparticles were prospected.

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