综述与专题评论

肽-金属离子螯合物的抑菌活性及抑菌机制研究进展

  • 夏冰 ,
  • 董艺帆 ,
  • 高先晶 ,
  • 段晓杰 ,
  • 布冠好 ,
  • 杨趁仙
展开
  • (河南工业大学,粮油食品学院省部级科研平台,河南 郑州,450001)
第一作者:硕士研究生(段晓杰讲师为通信作者,E-mail:duanxj@haut.edu.cn)

收稿日期: 2024-07-14

  修回日期: 2024-08-01

  网络出版日期: 2025-05-28

基金资助

河南省自然科学基金项目(232300420205);河南工业大学粮油食品学院省部级科研平台开放课题项目(GO202305);河南工业大学创新基金支持计划专项资助(2021ZKCJ03)

Research progress on antimicrobial activity and mechanism of peptide-metal ion chelates

  • XIA Bing ,
  • DONG Yifan ,
  • GAO Xianjing ,
  • DUAN Xiaojie ,
  • BU Guanhao ,
  • YANG Chenxian
Expand
  • (Food Engineering Technology Research Center/Key Laboratory of Henan Province, Henan University of Technology, Zhengzhou 450001, China)

Received date: 2024-07-14

  Revised date: 2024-08-01

  Online published: 2025-05-28

摘要

肽-金属离子螯合物是由肽和金属离子发生螯合反应形成的性质稳定的环状化合物,具备的抗菌活性使其在防止食品腐败变质方面展现出应用潜力。该文介绍了肽-金属离子螯合物的抑菌活性、结构与抑菌活性之间的关系,及其对不同靶标的作用机制,并总结了目前研究中肽-金属离子螯合物在食品防腐保鲜方面的应用,以期为具有抑菌活性的肽-金属离子螯合物的深入研究与开发提供参考。

本文引用格式

夏冰 , 董艺帆 , 高先晶 , 段晓杰 , 布冠好 , 杨趁仙 . 肽-金属离子螯合物的抑菌活性及抑菌机制研究进展[J]. 食品与发酵工业, 2025 , 51(9) : 351 -358 . DOI: 10.13995/j.cnki.11-1802/ts.040485

Abstract

Peptide-metal ion chelate is a stable cyclic compound formed by chelation reaction between peptide and metal ion.Peptide-metal ion chelates have been reported to possess antimicrobial activity, which makes them show application potential in preventing food spoilage.The present review provide a comprehensive overview of the antimicrobial activity, the relationship between structure and antimicrobial activity of peptide-metal ion chelates and the antimicrobial mechanism of their action on different targets.Finally, this paper summarize the application of peptide-metal ion chelates in food preservation based on the current research.It can provide a reference for the further research and development of peptide-metal ion chelates with antimicrobial activity.

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