[1] 曾鸿哲, 周方, 刘昌伟, 等.茶及其功能成分对肠道菌群调节作用的研究进展[J].中国茶叶加工, 2022(1):5-10.
ZENG H Z, ZHOU F, LIU C W, et al.Research progress on the regulatory effect of tea and its functional components on intestinal flora[J].China Tea Processing, 2022(1):5-10.
[2] 李丹. 黑茶对肠道菌群的调节作用研究[D].广州:华南农业大学, 2016.
LI D.The study of the regulating effect of dark tea on gut microbiota[D].Guangzhou:South China Agricultural University, 2016.
[3] HOU Y, ZHANG Z F, CUI Y S, et al.Pu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions[J].Food Research International, 2022, 162:112176.
[4] ZHANG X, ZHU X L, SUN Y K, et al.Fermentation in vitro of EGCG, GCG and EGCG3″Me isolated from Oolong tea by human intestinal microbiota[J].Food Research International, 2013, 54(2):1589-1595.
[5] KANG J Y, WANG Z W, CREMONINI E, et al.(-)-Epicatechin mitigates anxiety-related behavior in a mouse model of high fat diet-induced obesity[J].The Journal of Nutritional Biochemistry, 2022, 110:109158.
[6] ZHENG S J, HUANG K L, ZHAO C H, et al.Procyanidin attenuates weight gain and modifies the gut microbiota in high fat diet induced obese mice[J].Journal of Functional Foods, 2018, 49:362-368.
[7] DENG X J, ZHANG N, WANG Q, et al.Theabrownin of raw and ripened pu-erh tea varies in the alleviation of HFD-induced obesity via the regulation of gut microbiota[J].European Journal of Nutrition, 2023, 62(5):2177-2194.
[8] ZHEN Q C, LIANG Q J, WANG H C, et al.Theabrownin ameliorates liver inflammation, oxidative stress, and fibrosis in MCD diet-fed C57BL/6J mice[J].Frontiers in Endocrinology, 2023, 14:1118925.
[9] 代丽凤, 蒋洁琳, 官兴丽, 等.茶褐素理化性质及生物学活性研究进展[J].食品与机械, 2023, 39(6):227-233;240.
DAI L F, JIANG J L, GUAN X L, et al.Research progress on physicochemical properties and biological activity of theabrownin[J].Food & Machinery, 2023, 39(6):227-233;240.
[10] 蒋慧颖, 马玉仙, 曾文治, 等.茶黄素、茶红素与茶褐素对高脂饮食大鼠肠道菌群的影响[J].食品工业科技, 2018, 39(20):274-279;351.
JIANG H Y, MA Y X, ZENG W Z, et al.Effects of theaflavins, thearubigins and theabrownine on intestinal flora in rats fed with high-fat diet[J].Science and Technology of Food Industry, 2018, 39(20):274-279;351.
[11] YUE S J, SHAN B, PENG C X, et al.Theabrownin-targeted regulation of intestinal microorganisms to improve glucose and lipid metabolism in Goto-Kakizaki rats[J].Food & Function, 2022, 13(4):1921-1940.
[12] 谢志勇, 陈贵杰, 曾子琦, 等.安化黑茶调节肠道菌群功效及作用机理[J].中国茶叶, 2023, 45(11):1-9.
XIE Z Y, CHEN G J, ZENG Z Q, et al.Effect and mechanism of Anhua dark tea on regulating gut microbiota[J].China Tea, 2023, 45(11):1-9.
[13] 李焱, 林泳峰, 刘文美, 等.茶多糖研究的现状与发展趋势[J].茶叶科学, 2023, 43(4):447-459.
LI Y, LIN Y F, LIU W M, et al.Present status and development trends of research on tea polysaccharides[J].Journal of Tea Science, 2023, 43(4):447-459.
[14] BAI Y X, ZENG Z Q, XIE Z Y, et al.Effects of polysaccharides from Fuzhuan brick tea on immune function and gut microbiota of cyclophosphamide-treated mice[J].Journal of Nutritional Biochemistry, 2022, 101:108947.
[15] LI D L, CHENG Y K, ZENG X Q, et al.Polysaccharide from Ziyang selenium-enriched green tea prevents obesity and promotes adipose thermogenesis via modulating the gut microbiota[J].Journal of Agricultural and Food Chemistry, 2023, 71(36):13363-13375.
[16] YANG H, CAI R, KONG Z Y, et al.Teasaponin ameliorates murine colitis by regulating gut microbiota and suppressing the immune system response[J].Frontiers in Medicine, 2020, 7:584369.
[17] WANG S, HUANG X F, ZHANG P, et al.Dietary teasaponin ameliorates alteration of gut microbiota and cognitive decline in diet-induced obese mice[J].Scientific Reports, 2017, 7(1):12203.
[18] CHEN S N, KANG J X, ZHU H Q, et al.Tea seed saponins ameliorate cyclophosphamide-induced intestinal injury, immune disorder and gut microbial dysbiosis in mice[J].Food Bioscience, 2024, 57:103504.
[19] XU W, KONG Y Y, ZHANG T, et al.L-Theanine regulates lipid metabolism by modulating gut microbiota and bile acid metabolism[J].Journal of the Science of Food and Agriculture, 2023, 103(3):1283-1293.
[20] LIU S, WANG B, LIN L, et al.L-Theanine alleviates heat stress through modulation of gut microbiota and immunity[J].Journal of the Science of Food and Agriculture, 2024, 104(4):2059-2072.
[21] HE J, CHEN J, HE Q, et al.Oral L-theanine administration promotes fat browning and prevents obesity in mice fed high-fat diet associated with the modulation of gut microbiota[J].Journal of Functional Foods, 2021, 81:104476.
[22] WANG D X, CAI M, WANG T T, et al.Ameliorative effects of L-theanine on dextran sulfate sodium induced colitis in C57BL/6J mice are associated with the inhibition of inflammatory responses and attenuation of intestinal barrier disruption[J].Food Research International, 2020, 137:109409.
[23] 吴香兰, 刘仲华, 曹丹, 等.茯砖茶对小鼠肠道免疫功能调节作用的研究[J].茶叶科学, 2013, 33(2):125-130.
WU X L, LIU Z H, CAO D, et al.Effects of Fuzhuan brick tea on the adjustment of intestinal immune function in mice[J].Journal of Tea Science, 2013, 33(2):125-130.
[24] LONE J B, KOH W Y, PARRAY H A, et al.Gut microbiome:Microflora association with obesity and obesity-related comorbidities[J].Microbial Pathogenesis, 2018, 124:266-271.
[25] 杜海平. 肠AKK菌介导茯砖茶多糖调控脂肪产热功能的研究[D].西安:陕西师范大学, 2020.
DU H P.The gut Akkermansia muciniphila mediates the regulatory mechanism of Fu brick tea polysaccharide to exhibit the thermogenic function of adipocytes[D].Xi'an:Shaanxi Normal University, 2020.
[26] 代锦, 杨天兵, 陈良委, 等.藏茶水提物对高糖脂饮食小鼠血脂及其肠道菌群的影响分析[J].中国测试, 2023, 49(1):63-70.
DAI J, YANG T B, CHEN L W, et al.Effects of Tibetan tea water extract on blood lipids and gut flora in mice fed with high sugar and fat diet[J].China Measurement & Test, 2023, 49(1):63-70.
[27] 宋伟. 黑砖茶真菌的分离鉴定及功能研究[D].长沙:湖南农业大学, 2012.
SONG W.Research on isolation, identification and function of funguses in dark brick tea[D].Changsha:Hunan Agricultural University, 2012.
[28] 戴宇樵, 潘科, 李琴, 等.黑茶品质形成与功效研究进展[J].江苏农业科学, 2021, 49(10):24-29.
DAI Y Q, PAN K, LI Q, et al.Research progress in the quality formation and efficacy of dark tea[J].Jiangsu Agricultural Sciences, 2021, 49(10):24-29.
[29] HUANG F J, ZHENG X J, MA X H, et al.Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism[J].Nature Communications, 2019, 10(1):4971.
[30] 陶伟. 老鹰茶水提物改善高脂饮食诱导的小鼠肥胖作用及机制研究[D].重庆:重庆医科大学, 2023.
TAO W.Study on the effect and mechanism of hawk tea extract in improving high-fat diet-induced obesity in mice[D].Chongqing:Chongqing Medical University, 2023.
[31] 李秀平, 欧阳建, 唐静怡, 等.茯砖茶通过调节肠道菌群和胆汁酸代谢预防肥胖及高胆固醇血症作用机制[J].食品科学, 2022, 43(9):136-149.
LI X P, OUYANG J, TANG J Y, et al.Fuzhuan brick tea prevents obesity and hypercholesterolemia by regulating the intestinal flora and bile acid metabolism[J].Food Science, 2022, 43(9):136-149.
[32] ZHOU F, ZHU M Z, TANG J Y, et al.Six types of tea extracts attenuated high-fat diet-induced metabolic syndrome via modulating gut microbiota in rats[J].Food Research International, 2022, 161:111788.
[33] ZHU J X, WU M R, ZHOU H, et al.Liubao brick tea activates the PI3K-Akt signaling pathway to lower blood glucose, metabolic disorders and insulin resistance via altering the intestinal flora[J].Food Research International, 2021, 148:110594.
[34] 王景存, 田春雨, 张帆, 等.基于转录组学探讨滋肾清肝方改善2型糖尿病糖、脂代谢的作用机制[J].中国实验方剂学杂志, 2024, 30(8):109-117.
WANG J C, TIAN C Y, ZHANG F, et al.Mechanism of zishen Qinggan prescription in improving glucose and lipid metabolism in type 2 diabetes based on transcriptomics[J].Chinese Journal of Experimental Traditional Medical Formulae, 2024, 30(8):109-117.
[35] 尚露彤. 三种富硒茶与普通茶降血糖活性比较及机制初探[D].上海:上海师范大学, 2022.
SHANG L T.Comparative study on hypoglycemic activity and mechanism of three selenium-rich teas and regular tea[D].Shanghai:Shanghai Normal University, 2022.
[36] 周婷婷. 肠道菌群-胆汁酸-肝代谢轴与NAFLD的相关性及青砖茶干预作用研究[D].宜昌:三峡大学, 2021.
ZHOU T T.The correlation between gut microbiota-bile acid-liver metabolism axis and NAFLD and the intervention effect of Qingzhuan tea[D].Yichang:China Three Gorges University, 2021.
[37] BORRELLI A, BONELLI P, TUCCILLO F M, et al.Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma:Current and innovative therapeutic approaches[J].Redox Biology, 2018, 15:467-479.
[38] TRIPATHI A, DEBELIUS J, BRENNER D A, et al.The gut-liver axis and the intersection with the microbiome[J].Nature Reviews.Gastroenterology & Hepatology, 2018, 15(7):397-411.
[39] 周婷婷, 陈桂婷, 曹楠, 等.从肠道菌群改变探讨青砖茶对非酒精性脂肪肝的预防作用[J].茶叶科学, 2021, 41(5):669-680.
ZHOU T T, CHEN G T, CAO N, et al.Preventive effect of green brick tea on non-alcoholic fatty liver disease via gut microbiota changes[J].Journal of Tea Science, 2021, 41(5):669-680.
[40] LI B Y, MAO Q Q, XIONG R G, et al.Preventive effects of different black and dark teas on obesity and non-alcoholic fatty liver disease and modulate gut microbiota in high-fat diet fed mice[J].Foods, 2022, 11(21):3457.
[41] LI B Y, MAO Q Q, ZHOU D D, et al.Effects of tea against alcoholic fatty liver disease by modulating gut microbiota in chronic alcohol-exposed mice[J].Foods, 2021, 10(6):1232.
[42] YAN A W, FOUTS D E, BRANDL J, et al.Enteric dysbiosis associated with a mouse model of alcoholic liver disease[J].Hepatology, 2011, 53(1):96-105.
[43] 赵峰. 重组白细胞介素-2(IL-2)对固始鸡免疫机能和分泌型免疫球蛋白(SIgA)表达影响的研究[D].郑州:河南农业大学, 2008.
ZHAO F.Effects of recombinant interleukin-2 on immune function and SIgA expressions in Gushi chickens[D].Zhengzhou:Henan Agricultural University, 2008.
[44] 谭婷. 茯砖茶对急性UC小鼠肠道微生物菌群特异性变化的影响[D].长沙:湖南农业大学, 2017.
TAN T.Effects of Fu brick tea on the specific changes of intestinal microflora in mice with acute ulcerative colitis[D].Changsha:Hunan Agricultural University, 2017.
[45] FAVA F, DANESE S.Intestinal microbiota in inflammatory bowel disease:Friend of foe?[J].World Journal of Gastroenterology, 2011, 17(5):557-566.
[46] LIANG J, SHA S M, WU K C.Role of the intestinal microbiota and fecal transplantation in inflammatory bowel diseases[J].Journal of Digestive Diseases, 2014, 15(12):641-646.
[47] 柳岩. 茶叶提取物通过调节肠道微生物缓解葡聚糖硫酸钠诱导的小鼠结肠炎症[D].重庆:西南大学, 2020.
LIU Y.Tea extracts ameliorate dextran sulfate sodium-induced colitis in mice by modulating gut microbiota composition[D].Chongqing:Southwest University, 2020.
[48] 黄翔翔, 谭婷, 禹利君, 等.茯砖茶对葡聚糖硫酸钠诱导UC小鼠炎症及肠道微生物的影响[J].茶叶科学, 2021, 41(5):681-694.
HUANG X X, TAN T, YU L J, et al.Effects of fu brick tea on inflammation and intestinal microflora diversity in mice with DSS-induced ulcerative colitis[J].Journal of Tea Science, 2021, 41(5):681-694.
[49] 杨武奇. 茯砖茶茶褐素及结合态多酚缓解结肠炎的生化机制研究[D].西安:陕西师范大学, 2022.
YANG W Q.Study on the biochemical mechanism of theabrownin and bound polyphenols in Fuzhuan tea alleviating colitis[D].Xi'an:Shaanxi Normal University, 2022.
[50] 王昕. 茯砖茶中冠突曲霉对结肠炎小鼠的保护作用及机制研究[D].杨凌:西北农林科技大学, 2022.
WANG X.Protective effect of Aspergillus cristatus in Fuzhuan brick tea on colitis mice and its mechanism[D].Yangling:Northwest A&F University, 2022.
[51] 余智勇. 茯砖茶抗腹泻作用研究[D].长沙:湖南农业大学, 2010.
YU Z Y.Study of the anti-diarrhea effect of Fuzhuan tea[D].Changsha:Hunan Agricultural University, 2010.
[52] 姚亚丽. 茯砖茶抗腹泻活性部分筛选研究[D].长沙:湖南农业大学, 2012.
YAO Y L.Study on the screening for active parties of anti-diarrhea in Fuzhuan tea[D].Changsha:Hunan Agricultural University, 2012.
[53] 曾婷玉. 茯砖茶抗分泌性腹泻机制初探[D].长沙:湖南农业大学, 2013.
ZENG T Y.Primary exporation on the anti secretory diarrhea mechanisms of Fuzhuan tea[D].Changsha:Hunan Agricultural University, 2013.
[54] 鲍少华. 抗生素临床应用中存在的问题与对策分析[J].中医临床研究, 2014, 6(19):126-127.
BAO S H.A clinical policy and analysis of application of antibiotic[J].Clinical Journal of Chinese Medicine, 2014, 6(19):126-127.
[55] 傅冬和, 朱洺志, 刘仲华.安化黑茶调理肠胃功效及作用机理[J].中国茶叶, 2023, 45(3):1-7.
FU D H, ZHU M Z, LIU Z H.Effect and mechanism of Anhua dark tea on regulating gastrointestinal tract[J].China Tea, 2023, 45(3):1-7.
[56] 雷舒雯, 侯艳, 陈德洪, 等.普洱熟茶对D-半乳糖衰老模型小鼠肠道菌群的影响[J].食品科学, 2022, 43(7):120-127.
LEI S W, HOU Y, CHEN D H, et al.Effect of ripe Pu-erh tea on intestinal microorganisms in D-galactose-induced aging mice[J].Food Science, 2022, 43(7):120-127.
[57] SEN P, SHAH P P, NATIVIO R, et al.Epigenetic mechanisms of longevity and aging[J].Cell, 2016, 166(4):822-839.
[58] 兰兴成, 杨擎, 陈锡俊, 等.肠道菌群与衰老相关疾病研究进展[J].吉林中医药, 2020, 40(3):410-413.
LAN X C, YANG Q, CHEN X J, et al.Research progress of intestinal flora and aging-related diseases[J].Jilin Journal of Chinese Medicine, 2020, 40(3):410-413.
[59] 吴根梁, 侯爱香, 李珂, 等.陈年茯砖茶多酚类对老年人肠道菌群的影响研究[J].茶叶科学, 2018, 38(3):319-330.
WU G L, HOU A X, LI K, et al.Effects of polyphenols of old fu brick tea on the elderly intestinal flora[J].Journal of Tea Science, 2018, 38(3):319-330.