为探究低血糖生成指数(glycemic index,GI)枸杞杂粮代餐粉的最佳配方及降血糖作用,该研究以黄豆、绿豆、黑豆、燕麦、苦荞和藜麦6种杂粮作为主要原料,再辅以药食同源的宁夏枸杞制备一种低GI枸杞杂粮代餐粉。以感官评分为指标,采用单因素试验、Plackett-Burman试验、最陡爬坡试验及Box-Behnken试验,优化低GI枸杞杂粮代餐粉配方,并通过建立Ⅱ型糖尿病小鼠模型,评价低GI枸杞杂粮代餐粉的降血糖效果。结果表明,枸杞杂粮代餐粉最佳配方为:黄豆粉添加量15.1%,绿豆粉添加量15.1%,黑豆粉添加量14%,燕麦粉添加量15.6%,苦荞粉添加量12.1%,藜麦粉添加量12.1%,枸杞粉添加量16%(均为质量分数)。低GI枸杞杂粮代餐粉可下调小鼠餐后血糖值并能够改善小鼠基本生长状况,但使小鼠的空腹血糖值缓慢上升且整体趋于平稳状态(P>0.05)。
To explore the optimal formula and hypoglycemic effect of the low glycemic index (GI) barbary wolfberry of coarse grain meal replacement powder, in this study, six grains were used in soybean, mung bean, black bean, oats, Tartary buckwheat and quinoa as the main raw materials, and a low GI barbary wolfberry of coarse grain meal replacement powder was prepared from Ningxia barbary wolfberry with similar medicine and food.With the sensory score as an indicator, univariate test, Plackett-Burman test, steepest climbing test and Box-Behnken test were used to optimize the low GI barbary wolfberry coarse grain meal replacement powder formula, and the hypoglycemic effect of low GI barbary wolfberry coarse grain meal replacement powder was evaluated by establishing a type 2 diabetes mellitus mouse model.The results showed that the best formula of barbary wolfberry multigrain meal replacement powder was 15.1% of soybean flour, 15.1% of mung bean flour, 14% of black bean flour, 15.6% of oat flour, 12.1% of tartary buckwheat flour, 12.1% of quinoa flour, and 16% of barbary wolfberry flour.Low GI barbary wolfberry multigrain meal replacement powder improved the postprandial blood glucose value and improved the basic growth status of mice, but the fasting blood glucose value slowly increased and became overall stable (P>0.05).
[1] 王继红, 敬缠琴, 王珍, 等.小宗杂粮荞麦营养价值及栽培技术[J].农业科技与信息, 2022(3):25-28.
WANG J H, JING C Q, WANG Z, et al.Nutritional value and cultivation techniques of small multigrain buckwheat[J].Agricultural Science-Technology and Information, 2022(3):25-28.
[2] 彭欣, 戴霞, 秦林.论饮食“补养、调养、助养” 的营养学意义[J].辽宁中医杂志, 2015, 42(7):1214-1216.
PENG X, DAI X, QIN L.Study on tonifying, nursing and assisting role of diet in nutriology[J].Liaoning Journal of Traditional Chinese Medicine, 2015, 42(7):1214-1216.
[3] 刘敦华, 刘军, 李佩佩, 等.枸杞深加工产品开发现状及研究进展[J].食品科学技术学报, 2020, 38(4):10-20.
LIU D H, LIU J, LI P P, et al.Development status and research progress of deep processing products of Lycium barbarum[J].Journal of Food Science and Technology, 2020, 38(4):10-20.
[4] 张曼, 张美莉, 郭军.中国燕麦加工现状及产业发展趋势[J].农产品加工(学刊), 2014(8):49-51.
ZHANG M, ZHANG M L, GUO J.Oat processing status and development trend of the industry in China[J].Academic Periodical of Farm Products Processing, 2014(8):49-51.
[5] 郭琦. 燕麦高膳食纤维冲调粉的研制[D].太谷:山西农业大学, 2018.
GUO Q.Development of oat high dietary fiber mixing powder[D].Taigu:Shanxi Agricultural University, 2018.
[6] 黄小倩, 古远云, 陈辉, 等.控糖膳治疗2型糖尿病的临床研究[J].西南医科大学学报, 2021, 44(6):654-658.
HUANG X Q, GU Y Y, CHEN H, et al.A clinical study of glucose-controlling diet in the treatment of type 2 diabetes[J].Journal of Southwest Medical University, 2021, 44(6):654-658.
[7] YADAV S, VATS V, DHUNNOO Y, et al.Hypoglycemic and antihyperglycemic activity of Murraya koenigii leaves in diabetic rats[J].Journal of Ethnopharmacology, 2002, 82(2-3):111-116.
[8] 中华医学会糖尿病学分会. 中国糖尿病医学营养治疗指南(2013)[J].中华糖尿病杂志, 2015, 7(2):73-90.
Chinese Diabetes Society.Chinese guidelines for medical nutrition treatment of diabetes (2013)[J].Chinese Journal of Diabetes Mellitus, 2015, 7(2):73-90.
[9] MCKEOWN N M, MEIGS J B, LIU S M, et al.Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham offspring cohort[J].Diabetes Care, 2004, 27(2):538-546.
[10] 张园园. 低GI枸杞杂粮代餐粉的研制及其血糖调节作用研究[D].宁夏:宁夏大学,2022.
ZHANG Y Y.Development of low GI barbary wolfberry coarse grain meal replacement powder and its study on blood glucose regulation[D].Ningxia:Ningxia University, 2022.
[11] 阮有志, 宋小楠, 吴隆坤, 等.发芽大豆粉营养成分分析及其在蛋糕中的应用[J].现代食品, 2019(8):71-74;84.
RUAN Y Z, SONG X N, WU L K, et al.Quality changes of germinated soybean flour and its application in cake[J].Modern Food, 2019(8):71-74;84.
[12] 胡献国. 黄豆及豆制品的营养成分[J].中国保健食品, 2018.
HU X G.Nutrients of soybeans and soy products[J].Chinese Health Food, 2018.
[13] 王明海, 徐宁, 包淑英, 等.绿豆的营养成分及药用价值[J].现代农业科技, 2012(6):341-342.
WANG M H, XU N, BAO S Y, et al.Nutritional components and medical value of Vigna radiata L.Wilclzek[J].Modern Agricultural Science and Technology, 2012(6):341-342.
[14] 徐飞, 葛阳阳, 刘新春, 等.黑豆营养成分及生物活性的研究进展[J].中国食物与营养, 2019, 25(9):55-61.
XU F, GE Y Y, LIU X C, et al.Research advancement of nutritional composition and biological activiey of black soybean[J].Food and Nutrition in China, 2019, 25(9):55-61.
[15] GORINSTEIN S, LOJEK A, MILAN, et al.Comparison of composition and antioxidant capacity of some cereals and pseudocereals[J].International Journal of Food Science & Technology, 2008, 43(4):629-637.
[16] MÁRTON M, MÁNDOKI Z, CSAPÓ J.Evaluation of biological value of sprouts.I.Fat content, fatty acid composition[J].Acta Universitatis Sapientiae:Alimentaria, 2010, 3:53-65.
[17] 王静波. 苦荞复配酸奶的研制及其品质分析[D].成都:西华大学, 2013.
WANG J B.Development on compound yogurt of tartary buckwheat and it’s quality analysis[D].Chengdu:Xihua University, 2013.
[18] 宋毓雪, 黄凯丰.苦荞营养保健成分研究[J].安徽农业科学, 2011, 39(1):100-102.
SONG Y X, HUANG K F.Research on nourishing compositions of Fagopyrum tataricum[J].Journal of Anhui Agricultural Sciences, 2011, 39(1):100-102.
[19] 魏爱春, 杨修仕, 么杨, 等.藜麦营养功能成分及生物活性研究进展[J].食品科学, 2015, 36(15):272-276.
WEI A C, YANG X S, YAO Y, et al.Progress in research on nutritional and functional components and bioactivity of quinoa(Chenopodium quinoa Willd.)[J].Food Science, 2015, 36(15):272-276.
[20] 雷洁琼. 藜麦功能成分研究及利用[J].青海畜牧兽医杂志, 2016, 46(3):42-47.
LEI J Q.Research and utilization of functional components of quinoa[J].Chinese Qinghai Journal of Animal and Veterinary Sciences, 2016, 46(3):42-47.
[21] 丁玉静, 刘俊秀, 李金红, 等.黑果枸杞生理活性成分及作用研究进展[J].中国临床药理学杂志, 2017, 33(13):1280-1283.
DING Y J, LIU J X, LI J H, et al.Research progress of physiologically active ingredients and their functions of Lycium ruthenicum Murr[J].The Chinese Journal of Clinical Pharmacology, 2017, 33(13):1280-1283.
[22] 郑淑娟, 黄昆仑, 仝涛.橄榄苦苷对高脂饮食联合链脲佐菌素诱导的糖尿病小鼠的降血糖作用研究[J].食品安全质量检测学报, 2023, 14(3):43-49.
ZHENG S J, HUANG K L, TONG T.Hypoglycemic effect of oleuropein on diabetes mice induced by high-fat diet combined with streptozotocin[J].Journal of Food Safety & Quality, 2023, 14(3):43-49.
[23] 王司琪. 玉木耳膳食纤维的提取、表征及降血糖作用研究[D].长春:吉林农业大学, 2022.
WANG S Q.Extraction, characterization and hypoglycemic effect of Auricularia cornea Var.Li dietary fiber[D].Changchun:Jilin Agricultural University, 2022.