LI Guang-fu,CHEN Wei,LI Ting-ting,LU Zhong-yi
Food and Fermentation Industries. 2015, 41(2): 41.
To explore the anti-senile effect of Ganoderma lucidum polysaccharides (GLP)Probiotic Yogurt,D-galactose induced aging mice were fed with Probiotic Yogurt containing different proportion of GLP.Viscera index,SOD,CAT,GSH-Px activities and MDA contents in serum and tissue samples were measured.The results showed that SOD,CAT and GSH-Px activity were significantly increased and MDA content decreased in serum and tissue of male mice fed with GLP Probiotic Yogurt,while the high dose group [1 200 mg/(kg · d)] had the optimal results.Compared with the aging model group,in the group of male mice fed with 1 200 mg/(kg · d) of the GLP Probiotic Yogurt,SOD activities in serum,liver and brain were respectively increased by 20.34％,8.39％,48.95％,GSH-Px activities in serum and liver were respectively increased by 38.45％,39.67％,MDA contents in serum,liver and brain tissue were respectively reduced by 38.37％,43.97％,38.39％,CAT activities in the brain,liver and kidney were respectively increased by 60.02％,55.29％,37.73％.Compared with the yogurt group,SOD activities of the high dose group were respectively increased by 8.39％,1.58％,25.13％.Their GSH-Px activities wererespectively increased by 38.45％ and 39.67％.MDA contents were reduced by 43.97％,30.96％,and 18.91％,respectively.CAT activities were increased by 55.29％,32.07％ and 26.64％.In conclusion,the synergy of ganoderma lucidum polysaccharides (GLP) and probiotic yogurt could have a potential anti-aging function.
